1. Gene
  2. Tsg101 - tumor susceptibility 101 Gene

Tsg101 - tumor susceptibility 101 Gene

种属: Rattus norvegicus

同用名: Rw

基因 ID: 292925 | 基因类型: protein coding

关于 Tsg101

功能概要

Enables nuclear receptor coactivator activity. Involved in endosome to lysosome transport and protein monoubiquitination. Located in endosome membrane and nucleus. Human ortholog(s) of this gene implicated in breast cancer; breast carcinoma; cervix carcinoma; endometrial adenocarcinoma; and prostate Cancer. Orthologous to human TSG101 (tumor susceptibility 101). [provided by Alliance of Genome Resources, Apr 2022]

Tsg101 基因产物(1)

mRNA Protein Name
NM_181628.2 NP_853659.2 tumor susceptibility gene 101 protein
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables nuclear receptor coactivator activity IDA
IDA: 通过直接分析推断
14761944 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in endosome to lysosome transport IMP
IMP: 通过突变表型推断
19808888 RGD
involved in protein monoubiquitination IDA
IDA: 通过直接分析推断
14761944 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in endosome membrane IDA
IDA: 通过直接分析推断
11134028 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

tumor susceptibility gene 101 protein

ESCRT-I complex subunit TSG101

Tumor supressor

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Tsg101 NCBI NCBI:7251