Gata6 - GATA binding protein 6 Gene

种属: Rattus norvegicus

关于 Gata6

功能概要

Enables cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including positive regulation of BMP signaling pathway; positive regulation of cardiac muscle cell apoptotic process; and regulation of transcription by RNA polymerase II. Located in nucleus. Biomarker of congenital diaphragmatic hernia and pulmonary hypertension. Human ortholog(s) of this gene implicated in adenocarcinoma (multiple); congenital heart disease (multiple); and pancreatic hypoplasia-diabetes-congenital heart disease syndrome. Orthologous to human GATA6 (GATA binding protein 6). [provided by Alliance of Genome Resources, Apr 2022]