2. Gene
  3. Ndufc2 - NADH:ubiquinone oxidoreductase subunit C2 Gene

Ndufc2 - NADH:ubiquinone oxidoreductase subunit C2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 293130 | 基因类型: protein coding

关于 Ndufc2

功能概要

Involved in several processes, including mitochondrial respiratory chain complex I assembly; negative regulation of NIK/NF-kappaB signaling; and positive regulation of ATP biosynthetic process. Predicted to be located in mitochondrion. Predicted to be part of mitochondrial respiratory chain complex I. Human ortholog(s) of this gene implicated in nuclear type mitochondrial complex I deficiency. Orthologous to several human genes including NDUFC2 (NADH:ubiquinone oxidoreductase subunit C2). [provided by Alliance of Genome Resources, Apr 2022]

Ndufc2 基因产物(1)

mRNA Protein Name
NM_001009290.1 NP_001009290.1 NADH dehydrogenase [ubiquinone] 1 subunit C2
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in mitochondrial respiratory chain complex I assembly IMP
IMP: 通过突变表型推断
26888427 RGD
involved in negative regulation of non-canonical NF-kappaB signal transduction IMP
IMP: 通过突变表型推断
26888427 RGD
involved in negative regulation of reactive oxygen species biosynthetic process IMP
IMP: 通过突变表型推断
26888427 RGD
involved in positive regulation of ATP biosynthetic process IMP
IMP: 通过突变表型推断
26888427 RGD
involved in positive regulation of mitochondrial membrane potential IMP
IMP: 通过突变表型推断
26888427 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

NADH dehydrogenase [ubiquinone] 1 subunit C2

NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2, 14.5kDa

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS09156 NDUFC2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS21897 Ndufc2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS28414 Ndufc2 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ndufc2 NCBI NCBI:4718
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