1. Gene
  2. Pax2 - paired box 2 Gene

Pax2 - paired box 2 Gene

种属: Rattus norvegicus

同用名: Pax-2

基因 ID: 293992 | 基因类型: protein coding

关于 Pax2

功能概要

Predicted to enable C2H2 zinc finger domain binding activity; DNA-binding transcription factor activity, RNA polymerase II-specific; and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including aging; cellular response to epidermal growth factor stimulus; and positive regulation of cell population proliferation. Located in lysosome and nucleus. Biomarker of nephroblastoma. Human ortholog(s) of this gene implicated in focal segmental glomerulosclerosis 7 and renal coloboma syndrome. Orthologous to human PAX2 (paired box 2). [provided by Alliance of Genome Resources, Apr 2022]

Pax2 基因产物(1)

mRNA Protein Name
NM_001106361.1 NP_001099831.1 paired box protein Pax-2
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to epidermal growth factor stimulus IEP
IEP: 通过表达模式推断
11262416 RGD
involved in positive regulation of cell population proliferation IMP
IMP: 通过突变表型推断
15569307 RGD
involved in response to nutrient levels IEP
IEP: 通过表达模式推断
18639218 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

paired box protein Pax-2

paired box gene 2

paired box homeotic gene 2

paired box protein 2

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Pax2 NCBI NCBI:5076