2. Gene
  3. Ghrh - growth hormone releasing hormone Gene

Ghrh - growth hormone releasing hormone Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: GHRF

基因 ID: 29446 | 基因类型: protein coding

关于 Ghrh

功能概要

Enables growth hormone-releasing hormone activity. Involved in several processes, including circadian sleep/wake cycle, non-REM sleep; growth hormone secretion; and positive regulation of cell communication. Located in axon terminus; extracellular space; and perikaryon. Used to study myocardial infarction and prostatic hypertrophy. Biomarker of sleep disorder. Human ortholog(s) of this gene implicated in autoimmune polyendocrine syndrome type 1; endometrial cancer; ovarian cancer; and renal cell carcinoma. Orthologous to human GHRH (growth hormone releasing hormone). [provided by Alliance of Genome Resources, Apr 2022]

Ghrh 基因产物(1)

mRNA Protein Name
NM_031577.1 NP_113765.1 somatoliberin precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables growth hormone-releasing hormone activity IDA
IDA: 通过直接分析推断
12446584 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway IDA
IDA: 通过直接分析推断
12446584 RGD
involved in adenylate cyclase-modulating G protein-coupled receptor signaling pathway IDA
IDA: 通过直接分析推断
14664705 RGD
involved in cellular response to interleukin-6 IEP
IEP: 通过表达模式推断
19239705 RGD
involved in negative regulation of cardiac muscle cell apoptotic process IMP
IMP: 通过突变表型推断
19293247 RGD
involved in positive regulation of DNA-templated transcription IDA
IDA: 通过直接分析推断
14664705 RGD
involved in positive regulation of cAMP/PKA signal transduction IDA
IDA: 通过直接分析推断
10579333 RGD
involved in positive regulation of circadian sleep/wake cycle, non-REM sleep IMP
IMP: 通过突变表型推断
19889861 RGD
involved in positive regulation of cytosolic calcium ion concentration IDA
IDA: 通过直接分析推断
12213318 RGD
involved in positive regulation of cytosolic calcium ion concentration IMP
IMP: 通过突变表型推断
18363807 RGD
involved in positive regulation of growth hormone secretion IDA
IDA: 通过直接分析推断
6130528 RGD
involved in response to dexamethasone IEP
IEP: 通过表达模式推断
22067322 RGD
involved in response to hypoxia IEP
IEP: 通过表达模式推断
21180161 RGD
involved in response to leptin IEP
IEP: 通过表达模式推断
18806317 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in axon terminus IDA
IDA: 通过直接分析推断
6423368 RGD
located in extracellular space IDA
IDA: 通过直接分析推断
1537276 RGD
located in perikaryon IDA
IDA: 通过直接分析推断
6423368 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

somatoliberin

GRF

growth hormone-releasing factor

相关产品

Pre-clinical Phase
生物活性分子 (10)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-P3304 MR 409 Activator 99.51% 否
HY-P0089A Human growth hormone-releasing factor TFA 99.66% 否
HY-P3397A JV-1-36 acetate Antagonist 99.93% 否
HY-P0089 Human growth hormone-releasing factor / 否
HY-P3397 JV-1-36 Antagonist / 否
HY-P3594 [His1,Nle27] GHRF (1-32), amide, human / 否
HY-P3595 GHRF, porcine / 否
HY-RS05413 GHRH Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS16752 Ghrh Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23191 Ghrh Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ghrh NCBI NCBI:2691
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