Pou5f1 - POU class 5 homeobox 1 Gene

中文名称：POU 5 类同源框 1

种属: Rattus norvegicus

关于 Pou5f1

功能概要

该基因编码的蛋白可启动 DNA 结合转录激活剂活性，RNA 聚合酶 II 特异性；蛋白质结构域特异性结合活性；和序列特异性 DNA 结合活性。参与转录调控、DNA 模板化和对细胞因子的反应。位于核内。该基因的人类直系同源物与胚胎癌和精原细胞瘤有关。与包括 POU5F1（POU 5 类同源框 1）在内的几个人类基因同源。 [由基因组资源联盟提供，2022 年 4 月]

Enables DNA-binding transcription activator activity, RNA polymerase II-specific; protein domain specific binding activity; and sequence-specific DNA binding activity. Involved in regulation of transcription, DNA-templated and response to cytokine. Located in nucleus. Human ortholog(s) of this gene implicated in embryonal carcinoma and seminoma. Orthologous to several human genes including POU5F1 (POU class 5 homeobox 1). [provided by Alliance of Genome Resources, Apr 2022]