2. Gene
  3. Slc1a3 - solute carrier family 1 member 3 Gene

Slc1a3 - solute carrier family 1 member 3 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: EAAT1; GLAST; GluT-1; GLAST-1

基因 ID: 29483 | 基因类型: protein coding

关于 Slc1a3

功能概要

Enables high-affinity glutamate transmembrane transporter activity. Involved in L-aspartate import across plasma membrane; L-glutamate import across plasma membrane; and malate-aspartate shuttle. Acts upstream of or within L-glutamate transmembrane transport and response to inorganic substance. Located in several cellular components, including basolateral plasma membrane; dendritic spine; and neuronal cell body. Is integral component of plasma membrane. Part of membrane protein complex. Human ortholog(s) of this gene implicated in episodic ataxia type 6. Orthologous to human SLC1A3 (solute carrier family 1 member 3). [provided by Alliance of Genome Resources, Apr 2022]

Slc1a3 基因产物(4)

mRNA Protein Name
NM_001289941.1 NP_001276870.1 excitatory amino acid transporter 1 isoform 2
NM_001289942.1 NP_001276871.1 excitatory amino acid transporter 1 isoform 3
NM_001289943.1 NP_001276872.1 excitatory amino acid transporter 1 isoform 4
NM_019225.2 NP_062098.1 excitatory amino acid transporter 1 isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables L-glutamate transmembrane transporter activity IDA
IDA: 通过直接分析推断
15242733 RGD
enables glutamate:sodium symporter activity IMP
IMP: 通过突变表型推断
1279699 RGD
enables high-affinity L-glutamate transmembrane transporter activity IMP
IMP: 通过突变表型推断
1279699 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in L-aspartate import across plasma membrane IMP
IMP: 通过突变表型推断
1279699 RGD
involved in L-glutamate import across plasma membrane IMP
IMP: 通过突变表型推断
1279699 RGD
acts upstream of or within L-glutamate transmembrane transport IDA
IDA: 通过直接分析推断
7723632 RGD
involved in L-glutamate transmembrane transport IDA
IDA: 通过直接分析推断
15242733 RGD
involved in L-glutamate transmembrane transport IMP
IMP: 通过突变表型推断
10899959 RGD
involved in malate-aspartate shuttle IDA
IDA: 通过直接分析推断
15242733 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in basal plasma membrane IDA
IDA: 通过直接分析推断
26133720 RGD
located in basolateral plasma membrane IDA
IDA: 通过直接分析推断
9219972 RGD
located in dendritic spine IDA
IDA: 通过直接分析推断
11950769 RGD
part of membrane protein complex IDA
IDA: 通过直接分析推断
9334410 RGD
located in mitochondrial inner membrane IDA
IDA: 通过直接分析推断
15242733 RGD
located in neuron projection IDA
IDA: 通过直接分析推断
26133720 RGD
located in neuronal cell body IDA
IDA: 通过直接分析推断
26133720 RGD
located in plasma membrane IMP
IMP: 通过突变表型推断
1279699 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

excitatory amino acid transporter 1

glial glutamate transporter

glutamate transporter

glutamate/aspartate transporter

sodium-dependent glutamate/aspartate transporter 1

solute carrier family 1 (glial high affinity glutamate transporter), member 3

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS13054 SLC1A3 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS19528 Slc1a3 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26023 Slc1a3 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Slc1a3 NCBI NCBI:6507
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