2. Gene
  3. Krt18 - keratin 18 Gene

Krt18 - keratin 18 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Krt1-18

基因 ID: 294853 | 基因类型: protein coding

关于 Krt18

功能概要

Predicted to enable scaffold protein binding activity. Involved in several processes, including cholangiocyte apoptotic process; hepatocyte differentiation; and response to fructose. Located in several cellular components, including external side of plasma membrane; extracellular space; and keratin filament. Part of protein-containing complex. Biomarker of non-alcoholic fatty liver disease and non-alcoholic steatohepatitis. Human ortholog(s) of this gene implicated in liver cirrhosis. Orthologous to human KRT18 (keratin 18). [provided by Alliance of Genome Resources, Apr 2022]

Krt18 基因产物(1)

mRNA Protein Name
NM_053976.1 NP_446428.1 keratin, type I cytoskeletal 18
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cholangiocyte apoptotic process IEP
IEP: 通过表达模式推断
30563999 RGD
involved in hepatocyte differentiation IEP
IEP: 通过表达模式推断
24340101 RGD
involved in mesenchymal stem cell differentiation IEP
IEP: 通过表达模式推断
18484094 RGD
involved in response to fructose IEP
IEP: 通过表达模式推断
29989845 RGD
involved in response to nutrient levels IEP
IEP: 通过表达模式推断
24071521 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in external side of plasma membrane IDA
IDA: 通过直接分析推断
9353322 RGD
located in extracellular space IDA
IDA: 通过直接分析推断
24071521 RGD
located in keratin filament IDA
IDA: 通过直接分析推断
1709097 RGD
part of protein-containing complex IDA
IDA: 通过直接分析推断
9353322 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

keratin, type I cytoskeletal 18

CK-18

K18

cytokeratin-18

keratin 18, type I

keratin complex 1, acidic, gene 18

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS07441 KRT18 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS19704 Krt18 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26199 Krt18 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Krt18 NCBI NCBI:3875
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