1. Gene
  2. Pebp1 - phosphatidylethanolamine binding protein 1 Gene

Pebp1 - phosphatidylethanolamine binding protein 1 Gene

种属: Rattus norvegicus

同用名: Pbp; HCNP; Rkip

基因 ID: 29542 | 基因类型: protein coding

关于 Pebp1

功能概要

Enables ATP binding activity; mitogen-activated protein kinase binding activity; and receptor serine/threonine kinase binding activity. Involved in several processes, including positive regulation of acetylcholine metabolic process; positive regulation of mitotic nuclear division; and regulation of intracellular signal transduction. Located in several cellular components, including mitochondrial outer membrane; rough endoplasmic reticulum; and synaptic vesicle. Biomarker of myocardial infarction. Human ortholog(s) of this gene implicated in prostate Cancer. Orthologous to human PEBP1 (phosphatidylethanolamine binding protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Pebp1 基因产物(1)

mRNA Protein Name
NM_017236.2 NP_058932.1 phosphatidylethanolamine-binding protein 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables ATP binding IDA
IDA: 通过直接分析推断
10622376 RGD
enables kinase binding IPI
IPI: 通过物理相互作用推断
14654844 RGD
enables mitogen-activated protein kinase binding IDA
IDA: 通过直接分析推断
10490027 RGD
enables protein kinase binding IPI
IPI: 通过物理相互作用推断
11585904 RGD
enables receptor serine/threonine kinase binding IPI
IPI: 通过物理相互作用推断
27568556 RGD
enables signaling receptor binding IDA
IDA: 通过直接分析推断
10622376 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in MAPK cascade IDA
IDA: 通过直接分析推断
10490027 RGD
involved in eating behavior IEP
IEP: 通过表达模式推断
16132681 RGD
involved in hippocampus development IEP
IEP: 通过表达模式推断
18493952 RGD
involved in negative regulation of MAPK cascade IMP
IMP: 通过突变表型推断
15886202 RGD
involved in negative regulation of protein phosphorylation IMP
IMP: 通过突变表型推断
15886202 RGD
involved in positive regulation of acetylcholine biosynthetic process IDA
IDA: 通过直接分析推断
10622376 RGD
involved in positive regulation of acetylcholine metabolic process IDA
IDA: 通过直接分析推断
8888012 RGD
involved in positive regulation of cAMP/PKA signal transduction IMP
IMP: 通过突变表型推断
14654844 RGD
involved in positive regulation of mitotic nuclear division IMP
IMP: 通过突变表型推断
16916643 RGD
involved in regulation of the force of heart contraction IDA
IDA: 通过直接分析推断
16608915 RGD
involved in response to activity IEP
IEP: 通过表达模式推断
17963288 RGD
involved in response to cAMP IEP
IEP: 通过表达模式推断
7706975 RGD
involved in response to calcium ion IEP
IEP: 通过表达模式推断
10622376 RGD
involved in response to corticosterone IEP
IEP: 通过表达模式推断
18311602 RGD
involved in response to electrical stimulus IEP
IEP: 通过表达模式推断
11166120 RGD
involved in response to ethanol IEP
IEP: 通过表达模式推断
18067547 RGD
involved in response to oxidative stress IEP
IEP: 通过表达模式推断
18067547 RGD
involved in response to toxic substance IEP
IEP: 通过表达模式推断
11166120 RGD
involved in response to xenobiotic stimulus IEP
IEP: 通过表达模式推断
11166120 RGD
involved in spermatid development IEP
IEP: 通过表达模式推断
9508097 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in apical part of cell IDA
IDA: 通过直接分析推断
10639732 RGD
located in axon terminus IDA
IDA: 通过直接分析推断
11428049 RGD
located in cell surface IDA
IDA: 通过直接分析推断
11034991 RGD
located in extracellular space IDA
IDA: 通过直接分析推断
7706975 RGD
located in mitochondrial outer membrane IDA
IDA: 通过直接分析推断
11428049 RGD
located in neuronal cell body IDA
IDA: 通过直接分析推断
10622376 RGD
located in synaptic vesicle IDA
IDA: 通过直接分析推断
11428049 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

phosphatidylethanolamine-binding protein 1

23 kDa morphine-binding protein

HCNPpp

P23K

PEBP-1

Raf-1 kinase inhibitor protein

hippocampal cholinergic neurostimulating peptide

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Pebp1 NCBI NCBI:5037