1. Gene
  2. Kcnk3 - potassium two pore domain channel subfamily K member 3 Gene

Kcnk3 - potassium two pore domain channel subfamily K member 3 Gene

种属: Rattus norvegicus

同用名: rTASK; Task-1

基因 ID: 29553 | 基因类型: protein coding

关于 Kcnk3

功能概要

Enables open rectifier Potassium Channel activity and protein C-terminus binding activity. Involved in several processes, including cellular response to zinc ion; cochlea development; and negative regulation of cytosolic calcium ion concentration. Located in plasma membrane. Used to study pulmonary venoocclusive disease. Biomarker of status epilepticus. Human ortholog(s) of this gene implicated in primary pulmonary hypertension. Orthologous to human KCNK3 (potassium two pore domain channel subfamily K member 3). [provided by Alliance of Genome Resources, Apr 2022]

Kcnk3 基因产物(1)

mRNA Protein Name
NM_033376.2 NP_203694.1 potassium channel subfamily K member 3
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables open rectifier potassium channel activity IDA
IDA: 通过直接分析推断
9437008 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
12437930 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to hypoxia IMP
IMP: 通过突变表型推断
12215606 RGD
involved in cellular response to zinc ion IEP
IEP: 通过表达模式推断
9437008 RGD
involved in cochlea development IEP
IEP: 通过表达模式推断
15094499 RGD
involved in negative regulation of cytosolic calcium ion concentration IMP
IMP: 通过突变表型推断
16436472 RGD
involved in positive regulation of voltage-gated potassium channel activity IMP
IMP: 通过突变表型推断
31347976 RGD
involved in potassium ion transport IDA
IDA: 通过直接分析推断
15282272 RGD
involved in regulation of resting membrane potential IMP
IMP: 通过突变表型推断
31347976 RGD
involved in response to xenobiotic stimulus IEP
IEP: 通过表达模式推断
9437008 RGD
involved in response to xenobiotic stimulus IMP
IMP: 通过突变表型推断
14637154 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

potassium channel subfamily K member 3

TWIK-related acid-sensitive K(+) channel 1

TWIK-related acid-sensitive K+ channel

acid-sensitive potassium channel protein TASK-1

potassium channel, subfamily K, member 3

potassium channel, two pore domain subfamily K, member 3

two pore K(+) channel

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Kcnk3 NCBI NCBI:3777