2. Gene
  3. Bckdk - branched chain ketoacid dehydrogenase kinase Gene

Bckdk - branched chain ketoacid dehydrogenase kinase Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 29603 | 基因类型: protein coding

关于 Bckdk

功能概要

Enables ATP binding activity; [3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] kinase activity; and protein serine/threonine kinase activity. Involved in branched-chain amino acid catabolic process; phosphorylation; and spermatogenesis. Part of mitochondrial alpha-ketoglutarate dehydrogenase complex. Used to study branched-chain keto acid dehydrogenase kinase deficiency and oligospermia. Human ortholog(s) of this gene implicated in branched-chain keto acid dehydrogenase kinase deficiency. Orthologous to human BCKDK (branched chain keto acid dehydrogenase kinase). [provided by Alliance of Genome Resources, Apr 2022]

Bckdk 基因产物(1)

mRNA Protein Name
NM_019244.2 NP_062117.2 [3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables ATP binding IDA
IDA: 通过直接分析推断
1377677 RGD
enables [3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] kinase activity IMP
IMP: 通过突变表型推断
1377677 RGD
enables protein serine/threonine kinase activity IDA
IDA: 通过直接分析推断
1377677 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in L-leucine catabolic process IMP
IMP: 通过突变表型推断
27472223 RGD
involved in branched-chain amino acid catabolic process IDA
IDA: 通过直接分析推断
1377677 RGD
involved in isoleucine catabolic process IMP
IMP: 通过突变表型推断
27472223 RGD
involved in phosphorylation IDA
IDA: 通过直接分析推断
1377677 RGD
involved in spermatogenesis IMP
IMP: 通过突变表型推断
27472223 RGD
involved in valine catabolic process IMP
IMP: 通过突变表型推断
27472223 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of oxoglutarate dehydrogenase complex IDA
IDA: 通过直接分析推断
1377677 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial

BCKD-kinase

BCKDHKIN

branched-chain alpha-ketoacid dehydrogenase kinase

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS01411 BCKDK Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS19988 Bckdk Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26492 Bckdk Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Bckdk NCBI NCBI:10295
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