1. Gene
  2. Crhbp - corticotropin releasing hormone binding protein Gene

Crhbp - corticotropin releasing hormone binding protein Gene

种属: Rattus norvegicus

同用名: Crfbp

基因 ID: 29625 | 基因类型: protein coding

关于 Crhbp

功能概要

Enables corticotropin-releasing hormone binding activity. Involved in several processes, including cellular response to estrogen stimulus; cellular response to immobilization stress; and cellular response to organic cyclic compound. Located in several cellular components, including axon; cytoplasmic vesicle; and perikaryon. Biomarker of mental depression; obesity; and temporal lobe epilepsy. Human ortholog(s) of this gene implicated in mental depression. Orthologous to human CRHBP (corticotropin releasing hormone binding protein). [provided by Alliance of Genome Resources, Apr 2022]

Crhbp 基因产物(1)

mRNA Protein Name
NM_139183.2 NP_631922.1 corticotropin-releasing factor-binding protein precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables corticotropin-releasing hormone binding IDA
IDA: 通过直接分析推断
1846945 RGD
enables corticotropin-releasing hormone binding IPI
IPI: 通过物理相互作用推断
11572971 RGD
enables peptide binding IDA
IDA: 通过直接分析推断
11572971 RGD
enables peptide binding IPI
IPI: 通过物理相互作用推断
15223302 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to cocaine IDA
IDA: 通过直接分析推断
14751291 RGD
involved in cellular response to estradiol stimulus IDA
IDA: 通过直接分析推断
15345745 RGD
involved in cellular response to estrogen stimulus IDA
IDA: 通过直接分析推断
15345745 RGD
involved in cellular response to immobilization stress IDA
IDA: 通过直接分析推断
15530648 RGD
involved in hormone metabolic process IEP
IEP: 通过表达模式推断
15530648 RGD
involved in negative regulation of corticotropin secretion IDA
IDA: 通过直接分析推断
1846945 RGD
involved in synaptic transmission, dopaminergic IEP
IEP: 通过表达模式推断
18478589 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in axon terminus IDA
IDA: 通过直接分析推断
10524337 RGD
located in dendrite IDA
IDA: 通过直接分析推断
10524337 RGD
located in dense core granule IDA
IDA: 通过直接分析推断
10524337 RGD
located in extracellular space IDA
IDA: 通过直接分析推断
1846945 RGD
located in microtubule IDA
IDA: 通过直接分析推断
10524337 RGD
located in multivesicular body IDA
IDA: 通过直接分析推断
10524337 RGD
located in perikaryon IDA
IDA: 通过直接分析推断
10524337 RGD
located in secondary lysosome IDA
IDA: 通过直接分析推断
10524337 RGD
located in varicosity IDA
IDA: 通过直接分析推断
10524337 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

corticotropin-releasing factor-binding protein

CRF-BP

CRF-binding protein

CRH-BP

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Crhbp NCBI NCBI:1393