2. Gene
  3. DPM2 - Dpm2 dolichyl-phosphate mannosyltransferase subunit 2, regulatory Gene

DPM2 - Dpm2 dolichyl-phosphate mannosyltransferase subunit 2, regulatory Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 29640 | 基因类型: protein coding

关于 DPM2

功能概要

Enables dolichyl-phosphate beta-D-mannosyltransferase activity and enzyme regulator activity. Acts upstream of or within GPI anchor biosynthetic process and dolichol metabolic process. Located in perinuclear region of cytoplasm. Part of dolichol-phosphate-mannose synthase complex. Colocalizes with endoplasmic reticulum. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation Iu. Orthologous to human DPM2 (dolichyl-phosphate mannosyltransferase subunit 2, regulatory). [provided by Alliance of Genome Resources, Apr 2022]

DPM2 基因产物(1)

mRNA Protein Name
NM_019252.2 NP_062125.1 dolichol phosphate-mannose biosynthesis regulatory protein
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables dolichyl-phosphate beta-D-mannosyltransferase activity IDA
IDA: 通过直接分析推断
9724629 RGD
enables enzyme regulator activity IDA
IDA: 通过直接分析推断
9724629 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
10835346 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within GPI anchor biosynthetic process IDA
IDA: 通过直接分析推断
9724629 RGD
acts upstream of or within dolichol metabolic process IDA
IDA: 通过直接分析推断
9724629 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of dolichol-phosphate-mannose synthase complex IDA
IDA: 通过直接分析推断
9724629 RGD
located in endoplasmic reticulum IDA
IDA: 通过直接分析推断
9724629 RGD
located in perinuclear region of cytoplasm IDA
IDA: 通过直接分析推断
9724629 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

dolichol phosphate-mannose biosynthesis regulatory protein

DPM synthase subunit 2

dolichol-phosphate (beta-D) mannosyltransferase 2

dolichol-phosphate mannose synthase subunit 2

dolichol-phosphate mannosyltransferase 2

dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS03959 DPM2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS21326 Dpm2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS27845 Dpm2 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens DPM2 NCBI NCBI:8818
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