2. Gene
  3. CASK - Cask calcium/calmodulin dependent serine protein kinase Gene

CASK - Cask calcium/calmodulin dependent serine protein kinase Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 29647 | 基因类型: protein coding

关于 CASK

功能概要

Enables PDZ domain binding activity; neurexin family protein binding activity; and protein C-terminus binding activity. Involved in several processes, including nervous system development; positive regulation of Insulin secretion; and protein localization to plasma membrane. Located in several cellular components, including apical dendrite; basolateral plasma membrane; and podocyte foot. Part of protein-containing complex. Human ortholog(s) of this gene implicated in FG syndrome and syndromic X-linked intellectual disability Najm type. Orthologous to human CASK (calcium/Calmodulin dependent serine protein kinase). [provided by Alliance of Genome Resources, Apr 2022]

CASK 基因产物(1)

mRNA Protein Name
NM_022184.1 NP_071520.1 peripheral plasma membrane protein CASK
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables PDZ domain binding IPI
IPI: 通过物理相互作用推断
9660869 RGD
enables neurexin family protein binding IPI
IPI: 通过物理相互作用推断
8786425 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
9660869 RGD
enables protein kinase C binding IPI
IPI: 通过物理相互作用推断
17084383 RGD
enables protein-containing complex binding IPI
IPI: 通过物理相互作用推断
15331416 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cerebral cortex development IEP
IEP: 通过表达模式推断
10749215 RGD
involved in positive regulation of dendritic spine morphogenesis IMP
IMP: 通过突变表型推断
18606847 RGD
involved in positive regulation of insulin secretion IMP
IMP: 通过突变表型推断
24140090 RGD
involved in protein localization to plasma membrane IMP
IMP: 通过突变表型推断
14960569 RGD
involved in regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
19275891 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in apical dendrite IDA
IDA: 通过直接分析推断
9660869 RGD
located in basolateral plasma membrane IDA
IDA: 通过直接分析推断
10710551 RGD
located in ciliary membrane IDA
IDA: 通过直接分析推断
18596612 RGD
located in dendrite IDA
IDA: 通过直接分析推断
12641734 RGD
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
9660869 RGD
located in neuronal cell body IDA
IDA: 通过直接分析推断
9660869 RGD
located in nucleus IDA
IDA: 通过直接分析推断
18664494 RGD
located in perinuclear region of cytoplasm IDA
IDA: 通过直接分析推断
12641734 RGD
located in podocyte foot IDA
IDA: 通过直接分析推断
15994232 RGD
is active in postsynapse IDA
IDA: 通过直接分析推断
9660869 RGD
is active in postsynaptic density, intracellular component IDA
IDA: 通过直接分析推断
24753440 RGD
is active in presynapse IDA
IDA: 通过直接分析推断
9660869 RGD
located in presynaptic membrane IDA
IDA: 通过直接分析推断
18596612 RGD
part of protein-containing complex IDA
IDA: 通过直接分析推断
11356864 RGD
located in synaptic membrane IDA
IDA: 通过直接分析推断
8786425 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

peripheral plasma membrane protein CASK

calcium/calmodulin-dependent serine protein kinase (MAGUK family)

peripheral plasma membrane protein CASK-like

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-115719 CASK-IN-1 Inhibitor 99.7% 否
HY-RS01938 CASK Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18466 Cask Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24947 Cask Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens CASK NCBI NCBI:8573
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z