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  2. P2RX7 - purinergic receptor P2X 7 Gene

P2RX7 - purinergic receptor P2X 7 Gene

中文名称:嘌呤能受体 P2 X 7

种属: Rattus norvegicus

基因 ID: 29665 | 基因类型: protein coding

关于 P2RX7

Primary_assembly 12: 33,879,745-33,934,619 reverse strand.mRatBN7.2:CM026985.1

This gene has 6 transcripts (splice variants), 195 orthologues, 6 paralogues and is associated with 9 phenotypes. Biased expression in Liver (RPKM 74.), Lung (RPKM 67.2) and 9 other tissues.

功能概要

该基因编码的蛋白可启动多项功能,包括 ATP 绑定活动;细胞外 ATP 门控阳离子通道活性;和金属离子结合活性。涉及多个流程,包括ATP出口;气泡组装;和大分子代谢过程的正向调控。位于多个细胞成分中,包括泡;膜筏;和终端按钮。是核内膜的组成部分。部分含蛋白质复合物。与人 P2RX7(嘌呤能受体 P2X 7)同源。 [由基因组资源联盟提供,2022 年 4 月]

Enables several functions, including ATP binding activity; extracellularly ATP-gated cation channel activity; and metal ion binding activity. Involved in several processes, including ATP export; bleb assembly; and positive regulation of macromolecule metabolic process. Located in several cellular components, including bleb; membrane raft; and terminal bouton. Is integral component of nuclear inner membrane. Part of protein-containing complex. Orthologous to human P2RX7 (purinergic receptor P2X 7). [provided by Alliance of Genome Resources, Apr 2022]

P2RX7 基因产物(1)

mRNA Protein Name
NM_019256.2 NP_062129.1 P2X purinoceptor 7

P2RX7 蛋白结构

P2X_receptor

P2X_receptor: pfam00864 (10 - 412)

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  • 619 a.a.
蛋白主名 其他名称

P2X purinoceptor 7

ATP receptor

P2X purinoceptor 7-like

P2X7 purinoceptor

P2Z receptor

purinergic receptor P2X, ligand-gated ion channel, 7

purinergic receptor P2X7

直系同源

种属 基因名 来源 基因 ID
Homo sapiens P2RX7 NCBI NCBI:5027