2. Gene
  3. Gsn - gelsolin Gene

Gsn - gelsolin Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 296654 | 基因类型: protein coding

关于 Gsn

功能概要

Enables actin binding activity. Involved in several processes, including cellular response to cadmium ion; oligodendrocyte development; and phosphatidylinositol-mediated signaling. Located in several cellular components, including myelin sheath; perinuclear region of cytoplasm; and ruffle. Part of protein-containing complex. Biomarker of hypothyroidism and lung disease. Human ortholog(s) of this gene implicated in Finnish type amyloidosis. Orthologous to human GSN (gelsolin). [provided by Alliance of Genome Resources, Apr 2022]

Gsn 基因产物(1)

mRNA Protein Name
NM_001004080.1 NP_001004080.1 gelsolin precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables actin binding IDA
IDA: 通过直接分析推断
16280379 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in actin filament depolymerization IMP
IMP: 通过突变表型推断
11861757 RGD
involved in actin polymerization or depolymerization IDA
IDA: 通过直接分析推断
16280379 RGD
involved in cellular response to cadmium ion IDA
IDA: 通过直接分析推断
16280379 RGD
involved in oligodendrocyte development IEP
IEP: 通过表达模式推断
7817780 RGD
involved in positive regulation of cardiac muscle hypertrophy IMP
IMP: 通过突变表型推断
24505034 RGD
involved in positive regulation of p38MAPK cascade IMP
IMP: 通过突变表型推断
24505034 RGD
involved in response to ethanol IEP
IEP: 通过表达模式推断
12899944 RGD
involved in response to folic acid IEP
IEP: 通过表达模式推断
12899944 RGD
involved in tissue regeneration IEP
IEP: 通过表达模式推断
14574581 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in actin cytoskeleton IDA
IDA: 通过直接分析推断
16280379 RGD
located in apical ectoplasmic specialization IDA
IDA: 通过直接分析推断
11861757 RGD
located in basal ectoplasmic specialization IDA
IDA: 通过直接分析推断
11861757 RGD
located in extracellular space IDA
IDA: 通过直接分析推断
2829631 RGD
located in glial filament IDA
IDA: 通过直接分析推断
25744577 RGD
located in myelin sheath IDA
IDA: 通过直接分析推断
17960831 RGD
located in perinuclear region of cytoplasm IDA
IDA: 通过直接分析推断
16280379 RGD
part of protein-containing complex IDA
IDA: 通过直接分析推断
15823548 RGD
located in ruffle IDA
IDA: 通过直接分析推断
16280379 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

gelsolin

ADF

actin-depolymerizing factor

brevin

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-133870 Itaconate-alkyne 98.01% 否
HY-RS05867 GSN Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18449 Gsn Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24931 Gsn Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Gsn NCBI NCBI:2934
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