2. Gene
  3. Gabra5 - gamma-aminobutyric acid type A receptor subunit alpha 5 Gene

Gabra5 - gamma-aminobutyric acid type A receptor subunit alpha 5 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 29707 | 基因类型: protein coding

关于 Gabra5

功能概要

Enables GABA Receptor binding activity; GABA-A receptor activity; and transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential. Involved in brain development and chemical synaptic transmission. Located in dendrite and neuronal cell body membrane. Part of receptor complex. Is active in GABA-ergic synapse. Is integral component of postsynaptic specialization membrane and integral component of presynaptic membrane. Human ortholog(s) of this gene implicated in bipolar disorder; developmental and epileptic encephalopathy 79; and mental depression. Orthologous to human GABRA5 (gamma-aminobutyric acid type A receptor subunit alpha5). [provided by Alliance of Genome Resources, Apr 2022]

Gabra5 基因产物(1)

mRNA Protein Name
NM_017295.2 NP_058991.2 gamma-aminobutyric acid receptor subunit alpha-5 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables GABA receptor binding IPI
IPI: 通过物理相互作用推断
17959749 RGD
enables GABA-A receptor activity IDA
IDA: 通过直接分析推断
2153588 RGD
enables GABA-gated chloride ion channel activity IDA
IDA: 通过直接分析推断
10462548 RGD
enables transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential EXP
EXP: 通过实验结果推断
17951598 RGD
enables transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential IDA
IDA: 通过直接分析推断
17951598 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in chemical synaptic transmission IEP
IEP: 通过表达模式推断
15246695 RGD
involved in chemical synaptic transmission IMP
IMP: 通过突变表型推断
2153588 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in GABA-ergic synapse EXP
EXP: 通过实验结果推断
17951598 RGD
is active in GABA-ergic synapse IDA
IDA: 通过直接分析推断
16998906 RGD
located in dendrite IDA
IDA: 通过直接分析推断
15246695 RGD
located in neuronal cell body membrane IDA
IDA: 通过直接分析推断
15246695 RGD
is active in postsynaptic membrane IDA
IDA: 通过直接分析推断
16998906 RGD
is active in postsynaptic specialization membrane IDA
IDA: 通过直接分析推断
16998906 RGD
is active in presynaptic membrane IDA
IDA: 通过直接分析推断
16998906 RGD
part of receptor complex IDA
IDA: 通过直接分析推断
17959749 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

gamma-aminobutyric acid receptor subunit alpha-5

GABA(A) receptor subunit alpha-5

GABA-A receptor alpha-5 subunit

gamma-aminobutyric acid (GABA) A receptor, alpha 5

gamma-aminobutyric acid (GABA-A) receptor, subunit alpha 5

gamma-aminobutyric acid A receptor, alpha 5

gamma-aminobutyric acid type A

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS05213 GABRA5 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS21856 Gabra5 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS28373 Gabra5 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Gabra5 NCBI NCBI:2558
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z