Foxp1 - forkhead box P1 Gene

种属: Rattus norvegicus

关于 Foxp1

功能概要

Enables transcription cis-regulatory region binding activity. Involved in several processes, including cellular response to ionomycin; negative regulation of cell growth involved in cardiac muscle cell development; and positive regulation of hydrogen peroxide-induced cell death. Located in cytoplasm and nucleus. Biomarker of hepatocellular carcinoma; lung adenocarcinoma; and trichostrongyloidiasis. Human ortholog(s) of this gene implicated in several diseases, including Barrett's esophagus; congenital heart disease; esophagus adenocarcinoma; intellectual disability-severe speech delay-mild dysmorphism syndrome; and peritonitis. Orthologous to human FOXP1 (forkhead box P1). [provided by Alliance of Genome Resources, Apr 2022]