2. Gene
  3. Ndrg2 - N-myc downstream regulated gene 2 Gene

Ndrg2 - N-myc downstream regulated gene 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Ndr2; SYLD

基因 ID: 29811 | 基因类型: protein coding

关于 Ndrg2

功能概要

Acts upstream of or within negative regulation of ERK1 and ERK2 cascade; negative regulation of smooth muscle cell proliferation; and regulation of cytokine production. Located in cytoplasm and nucleus. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; musculoskeletal system; and respiratory system. Orthologous to human NDRG2 (NDRG family member 2). [provided by Alliance of Genome Resources, Apr 2022]

Ndrg2 基因产物(14)

mRNA Protein Name
NM_001145959.1 NP_001139431.1 protein NDRG2 isoform 2
NM_001360264.1 NP_001347193.1 protein NDRG2 isoform 3
NM_001360265.1 NP_001347194.1 protein NDRG2 isoform 1
NM_001360266.1 NP_001347195.1 protein NDRG2 isoform 1
NM_001360267.1 NP_001347196.1 protein NDRG2 isoform 1
NM_001360268.1 NP_001347197.1 protein NDRG2 isoform 1
NM_001360269.1 NP_001347198.1 protein NDRG2 isoform 1
NM_001360270.1 NP_001347199.1 protein NDRG2 isoform 4
NM_001360271.1 NP_001347200.1 protein NDRG2 isoform 2
NM_001360272.1 NP_001347201.1 protein NDRG2 isoform 2
NM_001360273.1 NP_001347202.1 protein NDRG2 isoform 2
NM_001360274.1 NP_001347203.1 protein NDRG2 isoform 2
NM_001360276.1 NP_001347205.1 protein NDRG2 isoform 2
NM_013864.2 NP_038892.1 protein NDRG2 isoform 1
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within negative regulation of ERK1 and ERK2 cascade IMP
IMP: 通过突变表型推断
19815093 MGI
acts upstream of or within negative regulation of cytokine production IMP
IMP: 通过突变表型推断
19815093 MGI
acts upstream of or within negative regulation of vascular associated smooth muscle cell proliferation IDA
IDA: 通过直接分析推断
16520977 MGI
acts upstream of or within regulation of platelet-derived growth factor production IMP
IMP: 通过突变表型推断
19815093 MGI
acts upstream of or within regulation of vascular endothelial growth factor production IMP
IMP: 通过突变表型推断
19815093 MGI
acts upstream of vascular associated smooth muscle cell proliferation IDA
IDA: 通过直接分析推断
16520977 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
16520977 MGI
located in nucleus IDA
IDA: 通过直接分析推断
16520977 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

protein NDRG2

N-myc downstream regulated 2

N-myc downstream-regulated gene 2 protein

protein Ndr2

相关产品

Pre-clinical Phase
生物活性分子 (7)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-P10359A TAT-QFNP12 acetate Inhibitor 95.90% 否
HY-100443 PX20606 Agonist / 否
HY-139418 PX20350 Agonist / 否
HY-P10359 TAT-QFNP12 Inhibitor / 否
HY-RS09115 NDRG2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS20061 Ndrg2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26565 Ndrg2 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ndrg2 NCBI NCBI:57447
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