1. Gene
  2. C8a - complement C8 alpha chain Gene

C8a - complement C8 alpha chain Gene

种属: Rattus norvegicus

基因 ID: 298288 | 基因类型: protein coding

关于 C8a

功能概要

Enables complement binding activity. Predicted to be involved in complement activation, classical pathway; cytolysis; and innate immune response. Predicted to act upstream of or within complement activation. Located in extracellular space. Biomarker of myocardial infarction. Human ortholog(s) of this gene implicated in type I Complement Component 8 deficiency. Orthologous to human C8A (complement C8 alpha chain). [provided by Alliance of Genome Resources, Apr 2022]

C8a 基因产物(1)

mRNA Protein Name
NM_001106670.1 NP_001100140.1 complement component C8 alpha chain precursor
基因本体论
  • 分子功能
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables complement binding IPI
IPI: 通过物理相互作用推断
3312411 RGD
enables protein-containing complex binding IPI
IPI: 通过物理相互作用推断
3312411 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular region IDA
IDA: 通过直接分析推断
3312411 RGD
located in extracellular space IDA
IDA: 通过直接分析推断
3312411 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

complement component C8 alpha chain

complement component 8 alpha subunit

complement component 8, alpha polypeptide

直系同源

种属 基因名 来源 基因 ID
Homo sapiens C8a NCBI NCBI:731
Macaca fascicularis C8a NCBI NCBI:102133722
Mus musculus C8a NCBI NCBI:230558