1. Gene
  2. Bok - BCL2 family apoptosis regulator BOK Gene

Bok - BCL2 family apoptosis regulator BOK Gene

种属: Rattus norvegicus

同用名: Bok-BH3

基因 ID: 29884 | 基因类型: protein coding

关于 Bok

功能概要

Enables BH domain binding activity and protein heterodimerization activity. Involved in several processes, including central nervous system development; male gonad development; and positive regulation of apoptotic process. Located in mitochondrion. Biomarker of hydrocephalus. Orthologous to human BOK (BCL2 family Apoptosis regulator BOK). [provided by Alliance of Genome Resources, Apr 2022]

Bok 基因产物(1)

mRNA Protein Name
NM_017312.2 NP_059008.1 bcl-2-related ovarian killer protein
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables BH domain binding IPI
IPI: 通过物理相互作用推断
9356461 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
9356461 RGD
enables protein dimerization activity IPI
IPI: 通过物理相互作用推断
9356461 RGD
NOT enables protein heterodimerization activity IDA
IDA: 通过直接分析推断
9804769 RGD
enables protein heterodimerization activity IDA
IDA: 通过直接分析推断
9804769 RGD
enables protein-containing complex binding IPI
IPI: 通过物理相互作用推断
9356461 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in apoptotic process IDA
IDA: 通过直接分析推断
9356461 RGD
involved in apoptotic process IMP
IMP: 通过突变表型推断
9356461 RGD
involved in male gonad development IEP
IEP: 通过表达模式推断
11720903 RGD
involved in oligodendrocyte differentiation IEP
IEP: 通过表达模式推断
12787069 RGD
involved in positive regulation of apoptotic process IDA
IDA: 通过直接分析推断
9356461 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

bcl-2-related ovarian killer protein

BCL2-related ovarian killer

BOK, BCL2 family apoptosis regulator

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Bok NCBI NCBI:666