2. Gene
  3. Dlst - dihydrolipoamide S-succinyltransferase Gene

Dlst - dihydrolipoamide S-succinyltransferase Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 299201 | 基因类型: protein coding

关于 Dlst

功能概要

Enables chaperone binding activity; dihydrolipoyllysine-residue succinyltransferase activity; and heat shock protein binding activity. Involved in 2-oxoglutarate metabolic process and NADH metabolic process. Located in mitochondrion and plasma membrane. Part of oxoglutarate dehydrogenase complex. Human ortholog(s) of this gene implicated in Alzheimer's disease and paraganglioma. Orthologous to human DLST (dihydrolipoamide S-succinyltransferase). [provided by Alliance of Genome Resources, Apr 2022]

Dlst 基因产物(1)

mRNA Protein Name
NM_001006981.2 NP_001006982.2 dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables dihydrolipoyllysine-residue succinyltransferase activity IDA
IDA: 通过直接分析推断
9405249 RGD
enables heat shock protein binding IPI
IPI: 通过物理相互作用推断
9811814 RGD
enables protein-folding chaperone binding IPI
IPI: 通过物理相互作用推断
9811814 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in 2-oxoglutarate metabolic process IDA
IDA: 通过直接分析推断
3571202 RGD
involved in NADH metabolic process IDA
IDA: 通过直接分析推断
9405249 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of oxoglutarate dehydrogenase complex IDA
IDA: 通过直接分析推断
3571202 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

2-oxoglutarate dehydrogenase complex component E2

E2

E2K

OGDC-E2

dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)

dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS03811 DLST Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18924 Dlst Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25414 Dlst Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Dlst NCBI NCBI:1743
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