1. Gene
  2. Amot - angiomotin Gene

Amot - angiomotin Gene

种属: Rattus norvegicus

同用名: RGD1564027

基因 ID: 300289 | 基因类型: protein coding

关于 Amot

功能概要

Predicted to enable angiostatin binding activity and signaling receptor activity. Predicted to be involved in several processes, including establishment of cell polarity involved in ameboidal cell migration; hippo signaling; and positive regulation of blood vessel endothelial cell migration. Predicted to act upstream of or within several processes, including gastrulation; negative regulation of GTPase activity; and vasculogenesis. Predicted to be located in several cellular components, including actin cytoskeleton; external side of plasma membrane; and ruffle. Predicted to be integral component of membrane. Predicted to be part of COP9 signalosome. Predicted to be active in several cellular components, including bicellular tight junction; cytoplasmic vesicle; and lamellipodium. Orthologous to human AMOT (angiomotin). [provided by Alliance of Genome Resources, Apr 2022]

Amot 基因产物(6)

mRNA Protein Name
XM_006257423.4 XP_006257485.2 angiomotin isoform X1
XM_006257420.4 XP_006257482.2 angiomotin isoform X1
XM_006257422.2 XP_006257484.2 angiomotin isoform X1
XM_006257421.2 XP_006257483.2 angiomotin isoform X1
XM_006257424.4 XP_006257486.2 angiomotin isoform X2
XM_039100625.1 XP_038956553.1 angiomotin isoform X2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
21481793 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in regulation of modification of postsynaptic actin cytoskeleton IDA
IDA: 通过直接分析推断
29317530 RGD
involved in regulation of modification of postsynaptic actin cytoskeleton IMP
IMP: 通过突变表型推断
29317530 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
29317530 RGD
is active in glutamatergic synapse IMP
IMP: 通过突变表型推断
29317530 RGD
is active in postsynaptic density IDA
IDA: 通过直接分析推断
29317530 RGD
is active in postsynaptic density IMP
IMP: 通过突变表型推断
29317530 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

angiomotin

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Amot NCBI NCBI:154796