1. Gene
  2. Abcb7 - ATP binding cassette subfamily B member 7 Gene

Abcb7 - ATP binding cassette subfamily B member 7 Gene

种属: Rattus norvegicus

基因 ID: 302395 | 基因类型: protein coding

关于 Abcb7

功能概要

Predicted to enable ABC-type iron-sulfur cluster transporter activity and protein homodimerization activity. Involved in cellular iron ion homeostasis and negative regulation of Reactive Oxygen Species biosynthetic process. Predicted to be located in mitochondrion. Predicted to be active in mitochondrial inner membrane. Predicted to be integral component of membrane. Human ortholog(s) of this gene implicated in X-linked sideroblastic anemia with ataxia. Orthologous to human ABCB7 (ATP binding cassette subfamily B member 7). [provided by Alliance of Genome Resources, Apr 2022]

Abcb7 基因产物(1)

mRNA Protein Name
NM_212518.1 NP_997683.1 iron-sulfur clusters transporter ABCB7, mitochondrial
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
31511561 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in intracellular iron ion homeostasis IDA
IDA: 通过直接分析推断
31511561 RGD
involved in negative regulation of reactive oxygen species biosynthetic process IMP
IMP: 通过突变表型推断
31511561 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

iron-sulfur clusters transporter ABCB7, mitochondrial

ABC transporter 7 protein

ATP-binding cassette transporter 7

ATP-binding cassette, sub-family B (MDR/TAP), member 7

ATP-binding cassette, sub-family B, member 7, mitochondrial

ATP-binding cassette, subfamily B (MDR/TAP), member 7

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Abcb7 NCBI NCBI:22