1. Gene
  2. Cpox - coproporphyrinogen oxidase Gene

Cpox - coproporphyrinogen oxidase Gene

种属: Rattus norvegicus

基因 ID: 304024 | 基因类型: protein coding

关于 Cpox

功能概要

Enables coproporphyrinogen oxidase activity and identical protein binding activity. Involved in several processes, including protoporphyrinogen IX biosynthetic process; response to lead ion; and response to methylmercury. Located in mitochondrial inner membrane and mitochondrial intermembrane space. Human ortholog(s) of this gene implicated in hereditary coproporphyria and liver disease. Orthologous to human CPOX (coproporphyrinogen oxidase). [provided by Alliance of Genome Resources, Apr 2022]

Cpox 基因产物(1)

mRNA Protein Name
NM_001037095.1 NP_001032172.1 oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables coproporphyrinogen oxidase activity IDA
IDA: 通过直接分析推断
11079369 RGD
enables identical protein binding IDA
IDA: 通过直接分析推断
11079369 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in heme biosynthetic process IDA
IDA: 通过直接分析推断
3955059 RGD
involved in protoporphyrinogen IX biosynthetic process IDA
IDA: 通过直接分析推断
3814086 RGD
involved in response to arsenic-containing substance IEP
IEP: 通过表达模式推断
2916235 RGD
involved in response to insecticide IEP
IEP: 通过表达模式推断
6626236 RGD
involved in response to iron ion IEP
IEP: 通过表达模式推断
2289051 RGD
involved in response to lead ion IEP
IEP: 通过表达模式推断
656697 RGD
involved in response to methylmercury IEP
IEP: 通过表达模式推断
2916235 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in mitochondrial inner membrane IDA
IDA: 通过直接分析推断
31872 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial

COX

coprogen oxidase

coproporphyrinogen-III oxidase, mitochondrial

coproporphyrinogenase

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cpox NCBI NCBI:1371