HBQ1 - hemoglobin subunit theta 1 Gene

中文名称：血红蛋白亚基 theta 1

种属: Homo sapiens

同用名: HBQ

基因 ID: 3049 | 基因类型: protein coding

关于 HBQ1

Cytogenetic location: 16p13.3 Genomic coordinates (GRCh38): 16:180,459-181,179 (from NCBI)

This gene has 1 transcript (splice variant), 79 orthologues and 11 paralogues.

功能概要

Theta-globin mRNA 存在于人胎儿红系组织中，但不存在于成人红系或其他非红系组织中。 theta-1 基因可能在胚胎生命的早期表达，可能在 5 周之前的某个时候。 Theta-1 是人类 α-珠蛋白基因簇的成员，涉及五个功能基因和两个假基因。基因的顺序是：5' - zeta - pseudozeta - mu - pseudoalpha-2 - pseudoalpha-1 - alpha-2 - alpha-1 - theta-1 - 3'。研究支持该基因的转录活性作用和肽在特定细胞 (可能是早期红细胞组织) 中的功能作用。[RefSeq 提供，2008 年 7 月]

Theta-globin mRNA is found in human fetal erythroid tissue but not in adult erythroid or Other nonerythroid tissue. The theta-1 gene may be expressed very early in embryonic life, perhaps sometime before 5 weeks. Theta-1 is a member of the human alpha-globin gene cluster that involves five functional genes and two pseudogenes. The order of genes is: 5' - zeta - pseudozeta - mu - pseudoalpha-2 -pseudoalpha-1 - alpha-2 - alpha-1 - theta-1 - 3'. Research supports a transcriptionally active role for the gene and a functional role for the peptide in specific cells, possibly those of early erythroid tissue. [provided by RefSeq, Jul 2008]

HBQ1 基因产物(1)

mRNA	Protein	Name
NM_005331.5	NP_005322.1	hemoglobin subunit theta-1

基因本体论

分子功能

分子功能 GO 注释	逻辑证据	参考文献	来源
enables protein binding	IPI IPI: 通过物理相互作用推断	25416956	GOA

EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

HBQ1 蛋白结构

Globin

0
100
142 a.a.

蛋白主名

其他名称

hemoglobin subunit theta-1

hemoglobin theta-1 chain

HBQ1 蛋白互作信息

分类	蛋白名称	蛋白编号	互作蛋白	互作蛋白种属	互作蛋白编号	实验方法	参考文献
种属内	HBQ1	P09105	RFESD	Homo sapiens	Q8TAC1	Y2H Array	31515488
种属内	HBQ1	P09105	RFESD	Homo sapiens	Q8TAC1	Y2H Prey Pooling	25416956
种属内	HBQ1	P09105	RFESD	Homo sapiens	Q8TAC1	Y2H Array	25416956
种属内	HBQ1	P09105	RFESD	Homo sapiens	Q8TAC1	Validated Y2H	25416956
种属内	HBQ1	P09105	RFESD	Homo sapiens	Q8TAC1	Validated Y2H	32296183
种属内	HBQ1	P09105	HBG2	Homo sapiens	P69892	Validated Y2H	32296183
种属内	HBQ1	P09105	HBD	Homo sapiens	P02042	Validated Y2H	25416956
种属内	HBQ1	P09105	HBD	Homo sapiens	P02042	Y2H Array	25416956
种属内	HBQ1	P09105	HBA1	Homo sapiens	P69905	Validated Y2H	32296183
种属内	HBQ1	P09105	HBA1	Homo sapiens	P69905	Y2H Prey Pooling	32296183
种属内	HBQ1	P09105	HBA1	Homo sapiens	P69905	Y2H Array	32296183
种属内	HBQ1	P09105	HBB	Homo sapiens	P68871	Validated Y2H	32296183
种属内	HBQ1	P09105	HBB	Homo sapiens	P68871	Y2H Prey Pooling	32296183
种属内	HBQ1	P09105	HBB	Homo sapiens	P68871	Y2H Array	32296183
种属内	HBQ1	P09105	NTAQ1	Homo sapiens	Q96HA8	Validated Y2H	32296183

种属间: 跨种属相互作用 种属内: 同种属相互作用

重组 HBQ1 蛋白

目录号	产品名	蛋白编号	纯度
HY-P70272	Hemoglobin subunit theta-1/HBQ1 Protein, Human (His)	P09105 (M1-R142)	≥95%

关联疾病

疾病名称

别名

Hemoglobin E Disease

Hemoglobin E

Hb-E Disease

Thalassemia

Sickle-Cell Thalassemia With Crisis	Sickle-Cell Thalassemia Without Crisis
Thalassemia Hb-S Disease With Crisis	Thalassemia Hb-S Disease Without Crisis
Thalassemias	Hereditary Leptocytosis
Haemoglobin Thalassaemia Disorder	Thalassaemia Syndrome
Thalassaemia Nos	Thalassemia Variants

Histiocytosis-Lymphadenopathy Plus Syndrome

H Syndrome	Histiocytosis With Joint Contractures And Sensorineural Deafness
Faisalabad Histiocytosis	Shml
Hjcd	Rosai-Dorfman Disease
Pigmented Hypertrichosis With Insulin-Dependent Diabetes Mellitus	Phid
Sinus Histiocytosis And Massive Lymphadenopathy	Familial Rosai-Dorfman Disease
Slc29a3 Spectrum Disorder	Sinus Histiocytosis With Massive Lymphadenopathy
Histiocytosis And Lymphadenopathy With Or Without Cutaneous, Cardiac, And/Or Endocrine Features, Joint Contractures, And/Or Deafness	Hyperpigmentation, Cutaneous, With Hypertrichosis, Hepatosplenomegaly, Heart Anomalies, And Hypogonadism With Or Without Hearing Loss
Rosai-Dorfman Disease, Familial	Cutaneous Hyperpigmentation With Hypertrichosis, Hepatosplenomegaly, Heart Anomalies, And Hypogonadism With Or Without Hearing Loss
Histiocytosis And Lymphadenopathy With Or Without Cutaneous, Cardiac, And/Or Endocrine Features, Joint Contractures And/Or Deafness	Rdd
Rosaï-Dorfman Disease	Slc29a3 Disorder
Destombes-Rosai-Dorfman Disease	Rosai-Dorfman-Destombes Disease
HLAS	Cutaneous Hyperpigmentation With Hypertrichosis Hepatosplenomegaly Heart Anomalies And Hypogonadism With Or Without Hearing Loss
Histiocytosis And Lymphadenopathy With Or Without Cutaneous Cardiac And/Or Endocrine Features Joint Contractures And/Or Deafness	H Disease
Sinus Histiocytosis

Hemoglobin H Disease

HBH	Hemoglobin H Disease, Nondeletional
Hemoglobin H Disease, Deletional	Alpha-Thalassemia Intermedia
Haemoglobin H Disease	Alpha-Thalassemia, Hemoglobin H Type
Hemoglobin H Disease, Deletional And Nondeletional	Alpha Thalassemia, Haemoglobin H Type
Alpha Thalassemia, Hemoglobin H Type	Haemoglobin H Disease, Deletional
Hbh Disease	Alpha-Thalassemia Hemoglobin H Type
Hemoglobin H Disease Deletional	Hemoglobin H Disease Non-Deletional
Alpha-Thalassemia	Alpha - /- - Or Mutational Forms Of Alpha-Thalassaemia
Alpha Thalassaemia Intermedia

Hemoglobin D Disease

Hb-D Disease	Punjab Disease
Los Angeles Disease	Hb D Los Angeles Disease
Hb D Punjab Disease

Fetal Hemoglobin Quantitative Trait Locus 1

Hereditary Persistence Of Fetal Hemoglobin	Delta-Beta-Thalassemia
Delta-Beta Thalassemia	Delta Beta-Thalassemia
HBFQTL1	Hemoglobin F, Hereditary Persistence Of
Hpfh	Hereditary Persistence Of Fetal Hemoglobin, Hb Gene Cluster-Related
Hemoglobin, Fetal, Quantitative Trait Locus 1	Hereditary Persistence Of Fetal Hemoglobin Thalassemia
Hpfh - [Hereditary Persistence Of Fetal Haemoglobin]	Fetal Haemoglobin
Persistence Of Fetal Haemoglobin	Persistent Haemoglobin F

Heinz Body Anemias

Heinz Body Anemia	Heinz Body Anemias, Alpha-
HEIBAN	Anemia, Heinz Body
Acquired Heinz Body Anemia

Hemoglobinopathy

Hemoglobinopathies

Congenital Hemolytic Anemia

Anemia Hemolytic Congenital	Anemia, Hemolytic, Congenital
Congenital Hemolytic Anaemia	Hereditary Hemolytic Anaemia
Hereditary Hemolytic Anemia

Beta-Thalassemia Major

Cooley'S Anemia	Cooley Anemia
Mediterranean Anemia

Alpha-Thalassemia

Alpha Thalassemia	Alpha Thalassaemia
Alpha Plus Thalassemia	Thalassemia, Alpha-
Thalassemias, Alpha-	A-Thalassemia
Α-Thalassemia	A-THAL
Thalassemia	Alpha Thalassaemia Syndrome

Hemoglobin C Disease

Hb C Disease	Hemoglobin C
Hb-C Disease

Alpha Thalassemia-Intellectual Disability Syndrome Type 1

Alpha Thalassemia-Intellectual Disability Syndrome, Deletion Type	Alpha-Thalassemia-Intellectual Disability Syndrome Linked To Chromosome 16
Atr Syndrome Linked To Chromosome 16	Atr Syndrome, Deletion Type
Atr-16 Syndrome	Alpha Thalassemia-Retardation Syndrome
Alpha-Thalassemia/Mental Retardation Syndrome, Deletion-Type	Alpha-Thalassemia/Mental Retardation Syndrome, Type 1
Alpha-Thalassemia Mental Retardation Syndrome, Deletion-Type

Hemolytic Anemia

Anemia, Hemolytic	Anemia Hemolytic
Anaemia Due To Other Disorders Of Glutathione Metabolism	Chronic Non Spherocytic Anaemia
G6pd - [Glucose-6-Phosphate Dehydrogenase Deficiency] Anaemia	Anaemia Due To Glucose-6-Phosphate Dehydrogenase Deficiency
Glucose-6-Phosphate Dehydrogenase Deficiency With Anaemia	Glucose-6-Phosphate Dehydrogenase Deficiency Anaemia
Favism Anaemia	Haemolytic Anaemia Due Tog6pd Deficiency
Favism	Pentose Phosphate Pathway Disorder Anaemia
Anaemia Due To Pentose Phosphate Pathway Defect

Sickle Cell Anemia

Hemoglobin Sc Disease	Anemia, Sickle Cell
Hbsc Disease	Sickle Cell-Hemoglobin C Disease Syndrome
Hb Ss Disease	Sickle Cell Trait
Drepanocytosis	Haemoglobin Sc Disease
Hb Sc Disease	Hb-S/Hb-C Disease
Hb-Ss Disease Without Crisis	Hemoglobin S Disease Without Crisis
Sickle Cell Anaemia	Sickle-Cell/Hb-C Disease Without Crisis
Sickle Cell - Hemoglobin C Disease	Hbs Disease
Hemoglobin S Disease	Sickling Disorder Due To Hemoglobin S
SKCA	Sickle Cell Disease
Sickle Cell-Hemoglobin C Disease	Sickle-Cell Disease Carrier
Sickle-Cell Heterozygous Disorder	Haemoglobin A-S Genotype
Hb-S - [Sickle Cell Haemoglobin] Carrier	Sickle Cell Haemoglobin Trait
As - [Sickle Cell Trait]	Hbas - [Sickle Cell Haemoglobin Trait]
Sickle-Cell Trait Haemoglobin Disease	Haemoglobin Sickle Cell Trait Disorder
Heterozygous Sickle Cell Trait	Hbas - [Heterozygous Haemoglobin S]

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-RS06034	HBQ1 Human Pre-designed siRNA Set A	Pre-designed Set	/	否
HY-RS25630	Hbq1 Rat Pre-designed siRNA Set A	Pre-designed Set	/	否

直系同源

种属	基因名	来源	基因 ID
Rattus norvegicus	HBQ1	RGD	RGD:2320907
Others	HBQ1	NCBI

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MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。

站点地图隐私声明

沪ICP备15051369号-4

上海工商

沪公网安备31011502019417

沪(浦)应急管危经许[2021]201709(QFYS)

营业执照（三证合一）

HBQ1 - hemoglobin subunit theta 1 Gene

关于 HBQ1

功能概要

HBQ1 基因产物(1)

HBQ1 蛋白结构

HBQ1 蛋白互作信息

重组 HBQ1 蛋白

关联疾病

直系同源

热门区域

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HBQ1 - hemoglobin subunit theta 1 Gene

关于 HBQ1

功能概要

HBQ1 基因产物(1)

HBQ1 蛋白结构

HBQ1 蛋白互作信息

重组 HBQ1 蛋白

关联疾病

相关产品

直系同源

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z