2. Gene
  3. Serpinc1 - serpin family C member 1 Gene

Serpinc1 - serpin family C member 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 304917 | 基因类型: protein coding

关于 Serpinc1

功能概要

Enables heparin binding activity and serine-type endopeptidase inhibitor activity. Involved in acute inflammatory response to antigenic stimulus; lactation; and response to nutrient. Located in extracellular space. Used to study thrombosis. Biomarker of familial hyperlipidemia; nephrotic syndrome; and ovarian Cancer. Human ortholog(s) of this gene implicated in Antithrombin III deficiency; disseminated intravascular coagulation; intermediate coronary syndrome; thrombosis; and toxic shock syndrome. Orthologous to human SERPINC1 (Serpin family C member 1). [provided by Alliance of Genome Resources, Apr 2022]

Serpinc1 基因产物(1)

mRNA Protein Name
NM_001012027.1 NP_001012027.1 antithrombin-III precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables heparin binding IDA
IDA: 通过直接分析推断
7362830 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
7362830 RGD
enables serine-type endopeptidase inhibitor activity IDA
IDA: 通过直接分析推断
7362830 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in acute inflammatory response to antigenic stimulus IEP
IEP: 通过表达模式推断
17850787 RGD
involved in lactation IEP
IEP: 通过表达模式推断
22776112 RGD
involved in response to nutrient IDA
IDA: 通过直接分析推断
17123684 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular space IDA
IDA: 通过直接分析推断
7930519 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

antithrombin-III

antithrombin III

serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1

serine (or cysteine) proteinase inhibitor, clade C (antithrombin), member 1

serpin peptidase inhibitor, clade C (antithrombin), member 1

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS12718 SERPINC1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18212 Serpinc1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24689 Serpinc1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Serpinc1 NCBI NCBI:462
Macaca fascicularis Serpinc1 NCBI NCBI:102117641
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