1. Gene
  2. CTNNA1 - Ctnna1 catenin alpha 1 Gene

CTNNA1 - Ctnna1 catenin alpha 1 Gene

种属: Rattus norvegicus

同用名: Catna1

基因 ID: 307505 | 基因类型: protein coding

关于 CTNNA1

功能概要

Predicted to enable several functions, including beta-catenin binding activity; cytoskeletal protein binding activity; and gamma-catenin binding activity. Involved in several processes, including gap junction assembly; gonad development; and response to estrogen. Located in acrosomal vesicle; adherens junction; and plasma membrane. Biomarker of esophageal Cancer and lung carcinoma. Human ortholog(s) of this gene implicated in patterned macular dystrophy 2. Orthologous to human CTNNA1 (catenin alpha 1). [provided by Alliance of Genome Resources, Apr 2022]

CTNNA1 基因产物(1)

mRNA Protein Name
NM_001007145.1 NP_001007146.1 catenin alpha-1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables beta-catenin binding IPI
IPI: 通过物理相互作用推断
12960056 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
12640114 RGD
enables protein-containing complex binding IPI
IPI: 通过物理相互作用推断
8834786 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in axon regeneration IEP
IEP: 通过表达模式推断
12387456 RGD
involved in gap junction assembly IMP
IMP: 通过突变表型推断
12577316 RGD
involved in male gonad development IEP
IEP: 通过表达模式推断
7507830 RGD
involved in odontogenesis of dentin-containing tooth IEP
IEP: 通过表达模式推断
10681393 RGD
involved in ovarian follicle development IEP
IEP: 通过表达模式推断
10864803 RGD
involved in response to estrogen IEP
IEP: 通过表达模式推断
10864803 RGD
involved in response to organic cyclic compound IEP
IEP: 通过表达模式推断
16678996 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in acrosomal vesicle IDA
IDA: 通过直接分析推断
16755864 RGD
located in adherens junction IDA
IDA: 通过直接分析推断
8834786 RGD
located in cell-cell junction IDA
IDA: 通过直接分析推断
15197645 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

catenin alpha-1

catenin (cadherin associated protein), alpha 1

catenin (cadherin-associated protein), alpha 1, 102kDa

catenin alpha-1-like

直系同源

种属 基因名 来源 基因 ID
Homo sapiens CTNNA1 NCBI NCBI:1495