2. Gene
  3. Itgb2 - integrin subunit beta 2 Gene

Itgb2 - integrin subunit beta 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Cd18

基因 ID: 309684 | 基因类型: protein coding

关于 Itgb2

功能概要

Contributes to cell adhesion molecule binding activity. Involved in several processes, including leukocyte migration; positive regulation of angiogenesis; and regulation of cellular biosynthetic process. Located in cell surface and plasma membrane. Used to study nephritis and pneumonia. Biomarker of allergic rhinitis. Human ortholog(s) of this gene implicated in coronary restenosis; leukocyte adhesion deficiency; and leukocyte adhesion deficiency 1. Orthologous to human ITGB2 (Integrin subunit beta 2). [provided by Alliance of Genome Resources, Apr 2022]

Itgb2 基因产物(1)

mRNA Protein Name
NM_001037780.2 NP_001032869.2 integrin beta-2 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
contributes to cell adhesion molecule binding IMP
IMP: 通过突变表型推断
16825578 RGD
enables protein-containing complex binding IPI
IPI: 通过物理相互作用推断
1672643 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cell-cell adhesion IMP
IMP: 通过突变表型推断
8938183 RGD
involved in cellular extravasation IMP
IMP: 通过突变表型推断
10363598 RGD
involved in endothelial cell migration IMP
IMP: 通过突变表型推断
16825578 RGD
involved in leukocyte cell-cell adhesion IMP
IMP: 通过突变表型推断
11804664 RGD
involved in leukocyte migration involved in inflammatory response IMP
IMP: 通过突变表型推断
10363598 RGD
involved in positive regulation of NF-kappaB transcription factor activity IMP
IMP: 通过突变表型推断
9062344 RGD
involved in positive regulation of angiogenesis IMP
IMP: 通过突变表型推断
16825578 RGD
involved in positive regulation of nitric oxide biosynthetic process IMP
IMP: 通过突变表型推断
9062344 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cell surface IDA
IDA: 通过直接分析推断
8938183 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

integrin beta-2

CD18 leukocyte adhesion molecule

integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1

integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1

macrophage antigen 1 (mac-1) beta subunit)

macrophage antige

相关产品

Clinical Phase
抗体抑制剂 (1)
目录号 产品名 作用方式
纯度 Phase
HY-P99946 Erlizumab Inhibitor / Phase 3
Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS06965 ITGB2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS16847 Itgb2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23288 Itgb2 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Itgb2 NCBI NCBI:3689
Mus musculus Itgb2 NCBI NCBI:16414
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z