1. Gene
  2. Kif5c - kinesin family member 5C Gene

Kif5c - kinesin family member 5C Gene

种属: Rattus norvegicus

基因 ID: 311024 | 基因类型: protein coding

关于 Kif5c

功能概要

Enables ATP hydrolysis activity; Apolipoprotein receptor binding activity; and microtubule binding activity. Involved in ATP metabolic process; anterograde axonal protein transport; and anterograde dendritic transport of messenger ribonucleoprotein complex. Located in dendrite. Human ortholog(s) of this gene implicated in complex cortical dysplasia with Other brain malformations 2 and schizophrenia. Orthologous to human KIF5C (Kinesin family member 5C). [provided by Alliance of Genome Resources, Apr 2022]

Kif5c 基因产物(1)

mRNA Protein Name
NM_001107730.1 NP_001101200.1 kinesin heavy chain isoform 5C
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables ATP hydrolysis activity IDA
IDA: 通过直接分析推断
7602588 RGD
enables apolipoprotein receptor binding IPI
IPI: 通过物理相互作用推断
11238452 RGD
enables microtubule binding IDA
IDA: 通过直接分析推断
7602588 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
19135897 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in anterograde axonal protein transport IMP
IMP: 通过突变表型推断
23576431 RGD
involved in intracellular mRNA localization IMP
IMP: 通过突变表型推断
23121659 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in GABA-ergic synapse IDA
IDA: 通过直接分析推断
20152113 RGD
located in dendrite IDA
IDA: 通过直接分析推断
22355657 RGD
is active in postsynaptic cytosol IDA
IDA: 通过直接分析推断
20152113 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

kinesin heavy chain isoform 5C

kinesin heavy chain neuron-specific 2

kinesin-1

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Kif5c NCBI NCBI:3800