1. Gene
  2. Spint1 - serine peptidase inhibitor, Kunitz type 1 Gene

Spint1 - serine peptidase inhibitor, Kunitz type 1 Gene

种属: Rattus norvegicus

同用名: HAI-1

基因 ID: 311331 | 基因类型: protein coding

关于 Spint1

功能概要

Enables serine-type endopeptidase inhibitor activity. Involved in cellular response to BMP stimulus; negative regulation of neural precursor cell proliferation; and positive regulation of glial cell differentiation. Located in plasma membrane. Biomarker of liver cirrhosis. Orthologous to human SPINT1 (serine peptidase inhibitor, Kunitz type 1). [provided by Alliance of Genome Resources, Apr 2022]

Spint1 基因产物(1)

mRNA Protein Name
NM_001004265.2 NP_001004265.2 kunitz-type protease inhibitor 1 precursor
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables serine-type endopeptidase inhibitor activity IMP
IMP: 通过突变表型推断
18048349 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to BMP stimulus IEP
IEP: 通过表达模式推断
23409135 RGD
involved in negative regulation of neural precursor cell proliferation IMP
IMP: 通过突变表型推断
23409135 RGD
involved in positive regulation of glial cell differentiation IMP
IMP: 通过突变表型推断
23409135 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

kunitz-type protease inhibitor 1

hepatocyte growth factor activator inhibitor-1

serine protease inhibitor, Kunitz type 1

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Spint1 NCBI NCBI:6692
Mus musculus Spint1 NCBI NCBI:20732