1. Gene
  2. Prex1 - phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 Gene

Prex1 - phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 Gene

种属: Rattus norvegicus

同用名: RGD1306534

基因 ID: 311647 | 基因类型: protein coding

关于 Prex1

功能概要

Predicted to enable phospholipid binding activity. Involved in positive regulation of cell migration; regulation of actin filament polymerization; and regulation of dendrite development. Located in several cellular components, including dendritic shaft; growth cone; and perinuclear region of cytoplasm. Orthologous to human PREX1 (phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1). [provided by Alliance of Genome Resources, Apr 2022]

Prex1 基因产物(1)

mRNA Protein Name
NM_001135718.2 NP_001129190.1 phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in positive regulation of cell migration IMP
IMP: 通过突变表型推断
15858067 RGD
involved in regulation of actin filament polymerization IMP
IMP: 通过突变表型推断
18697831 RGD
involved in regulation of dendrite development IMP
IMP: 通过突变表型推断
18697831 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in dendritic shaft IDA
IDA: 通过直接分析推断
18697831 RGD
located in growth cone IDA
IDA: 通过直接分析推断
18697831 RGD
located in perinuclear region of cytoplasm IDA
IDA: 通过直接分析推断
18697831 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Prex1 NCBI NCBI:57580