2. Gene
  3. Lrrc8a - leucine rich repeat containing 8 VRAC subunit A Gene

Lrrc8a - leucine rich repeat containing 8 VRAC subunit A Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Lrrc8

基因 ID: 311846 | 基因类型: protein coding

关于 Lrrc8a

功能概要

Enables volume-sensitive anion channel activity. Involved in aspartate transmembrane transport; response to osmotic stress; and taurine transport. Is integral component of plasma membrane. Human ortholog(s) of this gene implicated in agammaglobulinemia and agammaglobulinemia 5. Orthologous to human LRRC8A (leucine rich repeat containing 8 VRAC subunit A). [provided by Alliance of Genome Resources, Apr 2022]

Lrrc8a 基因产物(1)

mRNA Protein Name
NM_001024782.1 NP_001019953.1 volume-regulated anion channel subunit LRRC8A
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables volume-sensitive anion channel activity IMP
IMP: 通过突变表型推断
28833202 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in aspartate transmembrane transport IMP
IMP: 通过突变表型推断
28833202 RGD
involved in response to osmotic stress IMP
IMP: 通过突变表型推断
28833202 RGD
involved in taurine transmembrane transport IMP
IMP: 通过突变表型推断
28833202 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

volume-regulated anion channel subunit LRRC8A

leucine rich repeat containing 8 family, member A

leucine rich repeat containing 8A

leucine-rich repeat-containing 8

leucine-rich repeat-containing protein 8A

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS07827 LRRC8A Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS21148 Lrrc8a Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS27665 Lrrc8a Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Lrrc8a NCBI NCBI:56262
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z