2. Gene
  3. Eps15 - epidermal growth factor receptor pathway substrate 15 Gene

Eps15 - epidermal growth factor receptor pathway substrate 15 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: RGD1307641

基因 ID: 313474 | 基因类型: protein coding

关于 Eps15

功能概要

Predicted to enable identical protein binding activity and polyubiquitin modification-dependent protein binding activity. Involved in several processes, including endocytic recycling; positive regulation of receptor recycling; and postsynaptic neurotransmitter receptor internalization. Located in several cellular components, including apical plasma membrane; basal plasma membrane; and early endosome. Is active in glutamatergic synapse. Orthologous to human EPS15 (epidermal growth factor receptor pathway substrate 15). [provided by Alliance of Genome Resources, Apr 2022]

Eps15 基因产物(1)

mRNA Protein Name
NM_001365390.1 NP_001352319.1 epidermal growth factor receptor substrate 15
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
9920862 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in endocytic recycling IMP
IMP: 通过突变表型推断
21832070 RGD
involved in positive regulation of receptor recycling IMP
IMP: 通过突变表型推断
21832070 RGD
involved in postsynaptic neurotransmitter receptor internalization IDA
IDA: 通过直接分析推断
25023288 RGD
involved in postsynaptic neurotransmitter receptor internalization IEP
IEP: 通过表达模式推断
25023288 RGD
involved in postsynaptic neurotransmitter receptor internalization IMP
IMP: 通过突变表型推断
25023288 RGD
involved in regulation of cell population proliferation IMP
IMP: 通过突变表型推断
21832070 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in apical plasma membrane IDA
IDA: 通过直接分析推断
16625367 RGD
located in basal plasma membrane IDA
IDA: 通过直接分析推断
16625367 RGD
located in early endosome IDA
IDA: 通过直接分析推断
21832070 RGD
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
25023288 RGD
is active in glutamatergic synapse IMP
IMP: 通过突变表型推断
25023288 RGD
is active in postsynaptic endocytic zone IDA
IDA: 通过直接分析推断
35072626 RGD
is active in postsynaptic endocytic zone IMP
IMP: 通过突变表型推断
35072626 RGD
is active in synapse IDA
IDA: 通过直接分析推断
25023288 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

epidermal growth factor receptor substrate 15

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS04452 EPS15 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS04453 EPS15L1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS22489 Eps15 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS29012 Eps15 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Eps15 NCBI NCBI:2060
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