Tal1 - TAL bHLH transcription factor 1, erythroid differentiation factor Gene

种属: Rattus norvegicus

同用名: Tal-1

关于 Tal1

功能概要

Predicted to enable several functions, including E-box binding activity; histone deacetylase binding activity; and transmembrane receptor protein tyrosine kinase activator activity. Predicted to contribute to DNA binding activity. Predicted to be involved in several processes, including basophil differentiation; positive regulation of cellular component organization; and regulation of transcription, DNA-templated. Predicted to act upstream of or within several processes, including hemopoiesis; neurogenesis; and regulation of transcription by RNA polymerase II. Predicted to be located in chromatin and nucleoplasm. Predicted to be part of transcription regulator complex. Human ortholog(s) of this gene implicated in acute lymphoblastic leukemia. Orthologous to human TAL1 (TAL bHLH transcription factor 1, erythroid differentiation factor). [provided by Alliance of Genome Resources, Apr 2022]