2. Gene
  3. Rad21 - RAD21 cohesin complex component Gene

Rad21 - RAD21 cohesin complex component Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 314949 | 基因类型: protein coding

关于 Rad21

功能概要

Predicted to enable chromatin binding activity. Predicted to be involved in several processes, including nuclear division; regulation of cell cycle process; and replication-born double-strand break repair via sister chromatid exchange. Predicted to be located in chromosome and nuclear lumen. Predicted to be part of nuclear meiotic cohesin complex and nuclear mitotic cohesin complex. Predicted to be active in synaptonemal complex. Human ortholog(s) of this gene implicated in Cornelia de Lange syndrome 4; hepatocellular carcinoma; and lung non-small cell carcinoma. Orthologous to human RAD21 (RAD21 cohesin complex component). [provided by Alliance of Genome Resources, Apr 2022]

Rad21 基因产物(1)

mRNA Protein Name
NM_001025701.1 NP_001020872.1 double-strand-break repair protein rad21 homolog
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA-binding transcription factor binding IPI
IPI: 通过物理相互作用推断
36538854 RGD
enables lncRNA binding IDA
IDA: 通过直接分析推断
33741460 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in negative regulation of gene expression IMP
IMP: 通过突变表型推断
36538854 RGD
involved in negative regulation of glial cell apoptotic process IMP
IMP: 通过突变表型推断
36538854 RGD
involved in negative regulation of interleukin-1 beta production IMP
IMP: 通过突变表型推断
36538854 RGD
involved in negative regulation of neuron apoptotic process IMP
IMP: 通过突变表型推断
33741460 RGD
involved in negative regulation of tumor necrosis factor production IMP
IMP: 通过突变表型推断
36538854 RGD
involved in positive regulation of gene expression IMP
IMP: 通过突变表型推断
36538854 RGD
involved in positive regulation of interleukin-10 production IMP
IMP: 通过突变表型推断
36538854 RGD
involved in response to hypoxia IEP
IEP: 通过表达模式推断
33741460 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in nucleus IDA
IDA: 通过直接分析推断
36538854 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

double-strand-break repair protein rad21 homolog

RAD21 homolog

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-P10931F RAD21 (356–395), biotin labeled / 否
HY-RS11599 RAD21 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS20093 Rad21 Mouse Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS26596 Rad21 Rat Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Rad21 NCBI NCBI:5885
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