2. Gene
  3. Adsl - adenylosuccinate lyase Gene

Adsl - adenylosuccinate lyase Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 315150 | 基因类型: protein coding

关于 Adsl

功能概要

Enables (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido) succinate lyase (fumarate-forming) activity; N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity; and identical protein binding activity. Involved in several processes, including AMP biosynthetic process; response to hypoxia; and response to muscle activity. Located in cytosol. Biomarker of breast Cancer. Human ortholog(s) of this gene implicated in adenylosuccinase lyase deficiency. Orthologous to human ADSL (adenylosuccinate lyase). [provided by Alliance of Genome Resources, Apr 2022]

Adsl 基因产物(1)

mRNA Protein Name
NM_001130503.1 NP_001123975.1 adenylosuccinate lyase
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido) succinate lyase (fumarate-forming) activity IDA
IDA: 通过直接分析推断
3759987 RGD
enables N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity IDA
IDA: 通过直接分析推断
3689310 RGD
enables identical protein binding IPI
IPI: 通过物理相互作用推断
3689310 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in AMP biosynthetic process IDA
IDA: 通过直接分析推断
3759987 RGD
involved in aerobic respiration IMP
IMP: 通过突变表型推断
3777158 RGD
involved in response to hypoxia IEP
IEP: 通过表达模式推断
8887278 RGD
involved in response to muscle activity IEP
IEP: 通过表达模式推断
3777158 RGD
involved in response to nutrient IDA
IDA: 通过直接分析推断
7128902 RGD
involved in response to starvation IEP
IEP: 通过表达模式推断
690130 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

adenylosuccinate lyase

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS00418 ADSL Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18123 Adsl Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24597 Adsl Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Adsl NCBI NCBI:158
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