2. Gene
  3. Slc4a8 - solute carrier family 4 member 8 Gene

Slc4a8 - solute carrier family 4 member 8 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 315311 | 基因类型: protein coding

关于 Slc4a8

功能概要

Predicted to enable chloride transmembrane transporter activity and sodium:bicarbonate symporter activity. Predicted to be involved in bicarbonate transport; inorganic ion transmembrane transport; and regulation of intracellular pH. Predicted to act upstream of or within positive regulation of synaptic vesicle exocytosis and regulation of membrane potential. Located in several cellular components, including axon; glutamatergic synapse; and synaptic vesicle. Biomarker of prediabetes syndrome. Orthologous to human SLC4A8 (solute carrier family 4 member 8). [provided by Alliance of Genome Resources, Apr 2022]

Slc4a8 基因产物(3)

mRNA Protein Name
NM_001270794.1 NP_001257723.1 electroneutral sodium bicarbonate exchanger 1 isoform 2
NM_001270795.1 NP_001257724.1 electroneutral sodium bicarbonate exchanger 1 isoform 3
NM_199497.2 NP_955791.1 electroneutral sodium bicarbonate exchanger 1 isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables identical protein binding IDA
IDA: 通过直接分析推断
34584093 RGD
enables sodium,bicarbonate:chloride antiporter activity IDA
IDA: 通过直接分析推断
8189393 RGD
enables sodium,bicarbonate:chloride antiporter activity IMP
IMP: 通过突变表型推断
34584093 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in basolateral protein secretion IDA
IDA: 通过直接分析推断
21195699 RGD
involved in regulation of intracellular pH IDA
IDA: 通过直接分析推断
8189393 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in asymmetric synapse IDA
IDA: 通过直接分析推断
22102085 RGD
located in axon terminus IDA
IDA: 通过直接分析推断
22102085 RGD
located in basolateral plasma membrane IDA
IDA: 通过直接分析推断
18359573 RGD
located in glial cell projection IDA
IDA: 通过直接分析推断
22102085 RGD
located in glutamatergic synapse IDA
IDA: 通过直接分析推断
22102085 RGD
located in hippocampal mossy fiber IDA
IDA: 通过直接分析推断
22102085 RGD
located in neuron projection IDA
IDA: 通过直接分析推断
22102085 RGD
located in plasma membrane IDA
IDA: 通过直接分析推断
17715183 RGD
located in plasma membrane IMP
IMP: 通过突变表型推断
34584093 RGD
located in presynapse IDA
IDA: 通过直接分析推断
22102085 RGD
located in symmetric synapse IDA
IDA: 通过直接分析推断
22102085 RGD
located in synaptic vesicle IDA
IDA: 通过直接分析推断
22102085 RGD
located in synaptic vesicle membrane IDA
IDA: 通过直接分析推断
22102085 RGD
located in terminal bouton IDA
IDA: 通过直接分析推断
22102085 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

electroneutral sodium bicarbonate exchanger 1

Na-driven Cl-HCO3 exchanger NDCBE1-A

Na-driven Cl-HCO3 exchanger NDCBE1-B

Na-driven Cl-HCO3 exchanger NDCBE1-C

electroneutral Na+-driven Cl-HCO3 exchanger

k-NBC3

solute carrier family 4 (anion exchanger), member 8

solute carrier family 4, sodium bic

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS13273 SLC4A8 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS21937 Slc4a8 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS28453 Slc4a8 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Slc4a8 NCBI NCBI:9498
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