1. Gene
  2. Cd2ap - CD2-associated protein Gene

Cd2ap - CD2-associated protein Gene

种属: Rattus norvegicus

同用名: CMS

基因 ID: 316258 | 基因类型: protein coding

关于 Cd2ap

功能概要

Enables several functions, including beta-catenin binding activity; Cadherin binding activity; and protein C-terminus binding activity. Involved in several processes, including cell-cell adhesion; proteasome-mediated ubiquitin-dependent protein catabolic process; and regulation of receptor-mediated endocytosis. Located in cell leading edge; endocytic vesicle; and perinuclear region of cytoplasm. Part of protein-containing complex. Human ortholog(s) of this gene implicated in focal segmental glomerulosclerosis and focal segmental glomerulosclerosis 3. Orthologous to human CD2AP (CD2 associated protein). [provided by Alliance of Genome Resources, Apr 2022]

Cd2ap 基因产物(1)

mRNA Protein Name
NM_181475.3 NP_852140.2 CD2-associated protein
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables beta-catenin binding IDA
IDA: 通过直接分析推断
16617054 RGD
enables cadherin binding IPI
IPI: 通过物理相互作用推断
15910750 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
15001553 RGD
enables protein-containing complex binding IPI
IPI: 通过物理相互作用推断
16617054 RGD
enables vascular endothelial growth factor receptor binding IDA
IDA: 通过直接分析推断
15001553 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cell migration IMP
IMP: 通过突变表型推断
15910750 RGD
involved in cell-cell adhesion IMP
IMP: 通过突变表型推断
16617054 RGD
involved in proteasome-mediated ubiquitin-dependent protein catabolic process IDA
IDA: 通过直接分析推断
15001553 RGD
involved in regulation of receptor-mediated endocytosis IDA
IDA: 通过直接分析推断
15001553 RGD
involved in vesicle organization IDA
IDA: 通过直接分析推断
15001553 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cell leading edge IDA
IDA: 通过直接分析推断
15910750 RGD
located in endocytic vesicle IDA
IDA: 通过直接分析推断
15001553 RGD
located in perinuclear region of cytoplasm IDA
IDA: 通过直接分析推断
15910750 RGD
part of protein-containing complex IDA
IDA: 通过直接分析推断
16617054 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

CD2-associated protein

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cd2ap NCBI NCBI:23607