2. Gene
  3. Fus - Fus RNA binding protein Gene

Fus - Fus RNA binding protein Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 317385 | 基因类型: protein coding

关于 Fus

功能概要

Enables ionotropic glutamate receptor binding activity; Myosin V binding activity; and nuclear receptor binding activity. Involved in cellular response to calcium ion. Located in dendritic spine head; perikaryon; and perinuclear region of cytoplasm. Part of polysome. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis; amyotrophic lateral sclerosis type 6; essential tremor 4; liposarcoma; and neurodegenerative disease. Orthologous to human FUS (FUS RNA binding protein). [provided by Alliance of Genome Resources, Apr 2022]

Fus 基因产物(1)

mRNA Protein Name
NM_001012137.1 NP_001012137.1 RNA-binding protein FUS
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables ionotropic glutamate receptor binding IPI
IPI: 通过物理相互作用推断
19103256 RGD
enables myosin V binding IPI
IPI: 通过物理相互作用推断
19103256 RGD
enables nuclear estrogen receptor binding IDA
IDA: 通过直接分析推断
9440806 RGD
enables nuclear retinoid X receptor binding IPI
IPI: 通过物理相互作用推断
9440806 RGD
enables nuclear thyroid hormone receptor binding IDA
IDA: 通过直接分析推断
9440806 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to calcium ion IDA
IDA: 通过直接分析推断
19103256 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in dendrite IDA
IDA: 通过直接分析推断
15843054 RGD
located in dendritic spine IDA
IDA: 通过直接分析推断
15843054 RGD
located in dendritic spine head IDA
IDA: 通过直接分析推断
15843054 RGD
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
26834559 RGD
located in neuronal cell body IDA
IDA: 通过直接分析推断
15843054 RGD
located in perikaryon IDA
IDA: 通过直接分析推断
15843054 RGD
located in perinuclear region of cytoplasm IDA
IDA: 通过直接分析推断
15843054 RGD
is active in presynaptic cytosol IDA
IDA: 通过直接分析推断
26834559 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

RNA-binding protein FUS

16) in malignant liposarcoma)

16) malignant liposarcoma

fused in sarcoma RNA binding protein

fusion (involved in t(12

fusion, derived from t(12

fusion, derived from t(12

16) malignant liposarcoma

相关产品

Clinical Phase
生物活性分子 (2)
目录号 产品名 作用方式
纯度 Phase
HY-147410 Ulefnersen 94.55% Phase 3
HY-147410A Ulefnersen sodium 94.55% Phase 3
Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS05149 FUS Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS17359 Fus Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23813 Fus Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Fus NCBI NCBI:2521
Macaca fascicularis Fus NCBI NCBI:101925561
Mus musculus Fus NCBI NCBI:233908
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