2. Gene
  3. Syne2 - spectrin repeat containing, nuclear envelope 2 Gene

Syne2 - spectrin repeat containing, nuclear envelope 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: NUA; dice; Cpfl8; KASH2; Nesp2g; mKIAA1011; D12Ertd777e; 6820443O06Rik

基因 ID: 319565 | 基因类型: protein coding

关于 Syne2

功能概要

Enables actin binding activity. Involved in several processes, including centrosome localization; nuclear migration; and regulation of cilium assembly. Acts upstream of or within several processes, including fibroblast migration; nuclear envelope organization; and protein localization to nucleus. Located in Z disc and nuclear outer membrane. Is expressed in several structures, including alimentary system; brain; genitourinary system; integumental system; and sensory organ. Human ortholog(s) of this gene implicated in autosomal dominant Emery-Dreifuss muscular dystrophy 5. Orthologous to human SYNE2 (spectrin repeat containing nuclear envelope protein 2). [provided by Alliance of Genome Resources, Apr 2022]

Syne2 基因产物(2)

mRNA Protein Name
NM_001005510.2 NP_001005510.2 nesprin-2
NM_001005510.2 NP_001005510.2 nesprin-2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables actin binding IDA
IDA: 通过直接分析推断
20724637 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
24880667 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in centrosome localization IMP
IMP: 通过突变表型推断
19596800 MGI
involved in nuclear migration along microfilament IMP
IMP: 通过突变表型推断
20724637 MGI
involved in nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration IMP
IMP: 通过突变表型推断
19874786 MGI
involved in positive regulation of cell migration IMP
IMP: 通过突变表型推断
20724637 MGI
involved in regulation of cilium assembly IMP
IMP: 通过突变表型推断
19596800 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in Z disc IDA
IDA: 通过直接分析推断
15671068 MGI
located in myofibril IDA
IDA: 通过直接分析推断
15671068 MGI
located in nuclear envelope IDA
IDA: 通过直接分析推断
15671068 MGI
located in nuclear membrane IDA
IDA: 通过直接分析推断
22349700 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

nesprin-2

KASH domain-containing protein 2

diminished cone electroretinogram

nesprin 2

nuance

nuclear envelope spectrin repeat protein 2

nucleus and actin connecting element protein

synaptic nuclear envelope 2

synaptic nuclear envelope protein 2

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS14086 SYNE2 Human Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Syne2 NCBI NCBI:23224
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