1. Gene
  2. Igf2bp2 - insulin-like growth factor 2 mRNA binding protein 2 Gene

Igf2bp2 - insulin-like growth factor 2 mRNA binding protein 2 Gene

种属: Mus musculus

同用名: Imp2; IMP-2; Neilsen; C330012H03Rik

基因 ID: 319765 | 基因类型: protein coding

关于 Igf2bp2

功能概要

Predicted to enable mRNA 3'-UTR binding activity and mRNA 5'-UTR binding activity. Predicted to be involved in nervous system development; regulation of RNA metabolic process; and regulation of gene expression. Predicted to act upstream of or within mRNA transport and regulation of translation. Predicted to be located in Cytoskeleton. Predicted to be active in cytosol and nucleus. Is expressed in several structures, including alimentary system; early conceptus; gonad; liver; and otocyst. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to human IGF2BP2 (Insulin like growth factor 2 mRNA binding protein 2). [provided by Alliance of Genome Resources, Apr 2022]

Igf2bp2 基因产物(1)

mRNA Protein Name
NM_183029.2 NP_898850.2 insulin-like growth factor 2 mRNA-binding protein 2
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables mRNA 3'-UTR binding IDA
IDA: 通过直接分析推断
25863250 MGI
enables mRNA 5'-UTR binding IDA
IDA: 通过直接分析推断
25863250 MGI
enables translation regulator activity, nucleic acid binding IMP
IMP: 通过突变表型推断
25863250 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within cold-induced thermogenesis IMP
IMP: 通过突变表型推断
25863250 MGI
acts upstream of or within energy homeostasis IMP
IMP: 通过突变表型推断
25863250 MGI
involved in negative regulation of translation IMP
IMP: 通过突变表型推断
25863250 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

insulin-like growth factor 2 mRNA-binding protein 2

IGF-II mRNA-binding protein 2

IGF2 mRNA-binding protein 2

VICKZ family member 2

insulin-like growth factor 2, binding protein 2

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Igf2bp2 NCBI NCBI:10644
Macaca mulatta Igf2bp2 NCBI NCBI:700598