2. Gene
  3. Itpkb - inositol 1,4,5-trisphosphate 3-kinase B Gene

Itpkb - inositol 1,4,5-trisphosphate 3-kinase B Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: 1110033J02Rik; E130307H12Rik

基因 ID: 320404 | 基因类型: protein coding

关于 Itpkb

功能概要

Enables inositol-1,4,5-trisphosphate 3-kinase activity. Acts upstream of or within several processes, including common myeloid progenitor cell proliferation; negative regulation of neutrophil apoptotic process; and regulation of hemopoiesis. Located in cytosol; membrane; and nucleus. Is expressed in alimentary system; facial bone primordium; liver; nervous system; and urinary system. Orthologous to human ITPKB (inositol-trisphosphate 3-kinase B). [provided by Alliance of Genome Resources, Apr 2022]

Itpkb 基因产物(1)

mRNA Protein Name
NM_001081175.1 NP_001074644.1 inositol-trisphosphate 3-kinase B
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables inositol-1,4,5-trisphosphate 3-kinase activity IDA
IDA: 通过直接分析推断
14517551 MGI
enables inositol-1,4,5-trisphosphate 3-kinase activity IMP
IMP: 通过突变表型推断
15064401 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within MAPK cascade IMP
IMP: 通过突变表型推断
15064401 MGI
acts upstream of or within T cell differentiation IMP
IMP: 通过突变表型推断
14517551 MGI
acts upstream of or within cell surface receptor signaling pathway IMP
IMP: 通过突变表型推断
15064401 MGI
acts upstream of or within common myeloid progenitor cell proliferation IMP
IMP: 通过突变表型推断
18339802 MGI
acts upstream of or within myeloid cell homeostasis IMP
IMP: 通过突变表型推断
18339802 MGI
acts upstream of or within negative regulation of myeloid cell differentiation IMP
IMP: 通过突变表型推断
18339802 MGI
acts upstream of or within negative regulation of neutrophil apoptotic process IMP
IMP: 通过突变表型推断
18339802 MGI
acts upstream of or within positive regulation of Ras protein signal transduction IMP
IMP: 通过突变表型推断
15064401 MGI
acts upstream of or within positive regulation of alpha-beta T cell differentiation IMP
IMP: 通过突变表型推断
15064401 MGI
acts upstream of or within positive thymic T cell selection IMP
IMP: 通过突变表型推断
15064401 MGI
acts upstream of or within regulation of protein phosphorylation IMP
IMP: 通过突变表型推断
18339802 MGI
acts upstream of or within thymic T cell selection IMP
IMP: 通过突变表型推断
14517551 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytosol IDA
IDA: 通过直接分析推断
15381088 MGI
located in membrane IDA
IDA: 通过直接分析推断
15381088 MGI
located in nucleus IDA
IDA: 通过直接分析推断
15381088 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

inositol-trisphosphate 3-kinase B

相关产品

Pre-clinical Phase
生物活性分子 (5)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-126750 GNF362 Inhibitor 99.86% 否
HY-170506 KB-208 98.00% 否
HY-RS06989 ITPKB Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS19451 Itpkb Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25943 Itpkb Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Itpkb NCBI NCBI:3707
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