1. Gene
  2. Fan1 - FANCD2/FANCI-associated nuclease 1 Gene

Fan1 - FANCD2/FANCI-associated nuclease 1 Gene

种属: Mus musculus

同用名: mFAN1; Mtmr15; 6030441H18Rik

基因 ID: 330554 | 基因类型: protein coding

关于 Fan1

功能概要

Enables 5'-3' exonuclease activity. Predicted to be involved in double-strand break repair via homologous recombination; interstrand cross-link repair; and nucleotide-excision repair, DNA incision. Predicted to act upstream of or within cellular response to DNA damage stimulus. Predicted to be located in cytosol; intercellular bridge; and nucleoplasm. Predicted to be active in nucleus. Is expressed in ductus deferens; epididymis; and testis. Used to study karyomegalic interstitial nephritis. Human ortholog(s) of this gene implicated in karyomegalic interstitial nephritis. Orthologous to human FAN1 (FANCD2 and FANCI associated nuclease 1). [provided by Alliance of Genome Resources, Apr 2022]

Fan1 基因产物(1)

mRNA Protein Name
NM_177893.4 NP_808561.2 fanconi-associated nuclease 1
蛋白主名 其他名称

fanconi-associated nuclease 1

coiled-coil domain-containing protein MTMR15

myotubularin-related protein 15

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Fan1 NCBI NCBI:22909