2. Gene
  3. Card9 - caspase recruitment domain family, member 9 Gene

Card9 - caspase recruitment domain family, member 9 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Gm782

基因 ID: 332579 | 基因类型: protein coding

关于 Card9

功能概要

Enables CARD domain binding activity. Involved in several processes, including Antifungal innate immune response; host-mediated regulation of intestinal microbiota composition; and positive regulation of cytokine production. Acts upstream of or within several processes, including positive regulation of JNK cascade; regulation of cytokine production; and response to bacterium. Part of CBM complex. Human ortholog(s) of this gene implicated in chronic mucocutaneous candidiasis. Orthologous to human CARD9 (Caspase recruitment domain family member 9). [provided by Alliance of Genome Resources, Apr 2022]

Card9 基因产物(1)

mRNA Protein Name
NM_001037747.3 NP_001032836.1 caspase recruitment domain-containing protein 9
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables CARD domain binding IPI
IPI: 通过物理相互作用推断
22265677 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
17187069 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of JNK cascade IMP
IMP: 通过突变表型推断
17187069 MGI
involved in antifungal innate immune response IDA
IDA: 通过直接分析推断
22265677 MGI
involved in antifungal innate immune response IMP
IMP: 通过突变表型推断
24470469 MGI
acts upstream of or within defense response to Gram-positive bacterium IMP
IMP: 通过突变表型推断
17187069 MGI
acts upstream of or within defense response to virus IMP
IMP: 通过突变表型推断
17187069 MGI
involved in host-mediated regulation of intestinal microbiota composition IMP
IMP: 通过突变表型推断
23732773 MGI
involved in immunoglobulin mediated immune response IMP
IMP: 通过突变表型推断
33548172 MGI
acts upstream of interleukin-6 production IMP
IMP: 通过突变表型推断
17187069 MGI
acts upstream of macrophage cytokine production IMP
IMP: 通过突变表型推断
17187069 MGI
involved in neutrophil mediated immunity IMP
IMP: 通过突变表型推断
25621893 MGI
involved in positive regulation of ERK1 and ERK2 cascade IMP
IMP: 通过突变表型推断
25267792 MGI
acts upstream of or within positive regulation of JNK cascade IMP
IMP: 通过突变表型推断
17187069 MGI
involved in positive regulation of NF-kappaB transcription factor activity IDA
IDA: 通过直接分析推断
22265677 MGI
NOT acts upstream of or within positive regulation of NF-kappaB transcription factor activity IMP
IMP: 通过突变表型推断
17187069 MGI
involved in positive regulation of NF-kappaB transcription factor activity IMP
IMP: 通过突变表型推断
29080677 MGI
involved in positive regulation of T-helper 17 type immune response IMP
IMP: 通过突变表型推断
24470469 MGI
involved in positive regulation of chemokine production IMP
IMP: 通过突变表型推断
24470469 MGI
involved in positive regulation of cytokine production IDA
IDA: 通过直接分析推断
22265677 MGI
involved in positive regulation of cytokine production IMP
IMP: 通过突变表型推断
26679537 MGI
involved in positive regulation of cytokine production involved in inflammatory response IMP
IMP: 通过突变表型推断
25267792 MGI
acts upstream of or within positive regulation of innate immune response IMP
IMP: 通过突变表型推断
17187069 MGI
acts upstream of or within positive regulation of interleukin-6 production IMP
IMP: 通过突变表型推断
17187069 MGI
acts upstream of or within positive regulation of macrophage cytokine production IMP
IMP: 通过突变表型推断
17187069 MGI
acts upstream of or within positive regulation of stress-activated MAPK cascade IMP
IMP: 通过突变表型推断
17187069 MGI
involved in positive regulation of stress-activated MAPK cascade IMP
IMP: 通过突变表型推断
29080677 MGI
acts upstream of or within positive regulation of tumor necrosis factor production IMP
IMP: 通过突变表型推断
17187069 MGI
acts upstream of or within regulation of interleukin-2 production IMP
IMP: 通过突变表型推断
16862125 MGI
acts upstream of or within regulation of interleukin-6 production IMP
IMP: 通过突变表型推断
16862125 MGI
acts upstream of or within regulation of tumor necrosis factor production IMP
IMP: 通过突变表型推断
16862125 MGI
acts upstream of or within response to exogenous dsRNA IMP
IMP: 通过突变表型推断
17187069 MGI
acts upstream of or within response to fungus IMP
IMP: 通过突变表型推断
16862125 MGI
acts upstream of or within response to muramyl dipeptide IMP
IMP: 通过突变表型推断
17187069 MGI
acts upstream of or within response to peptidoglycan IMP
IMP: 通过突变表型推断
17187069 MGI
acts upstream of or within response to xenobiotic stimulus IMP
IMP: 通过突变表型推断
17187069 MGI
acts upstream of stress-activated MAPK cascade IMP
IMP: 通过突变表型推断
17187069 MGI
acts upstream of tumor necrosis factor production IMP
IMP: 通过突变表型推断
17187069 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of CBM complex IDA
IDA: 通过直接分析推断
22265677 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

caspase recruitment domain-containing protein 9

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-115497 BRD5529 Inhibitor 98.94% 否
HY-RS01923 CARD9 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18055 Card9 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24530 Card9 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Card9 NCBI NCBI:64170
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