2. Gene
  3. FFAR4 - free fatty acid receptor 4 Gene

FFAR4 - free fatty acid receptor 4 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：游离脂肪酸受体 4

种属: Homo sapiens

同用名: GT01; PGR4; BMIQ10; GPR120; GPR129; O3FAR1

基因 ID: 338557 | 基因类型: protein coding

关于 FFAR4

Cytogenetic location: 10q23.33 Genomic coordinates (GRCh38): 10:93,566,665-93,590,072 (from NCBI)

This gene has 3 transcripts (splice variants), 127 orthologues, 16 paralogues and is associated with 1 phenotype. Biased expression in colon (RPKM 6.8), fat (RPKM 2.6) and 2 other tissues.

功能概要

该基因编码属于 GPR 视紫红质家族的 G 蛋白偶联受体 (GPR) 。编码的蛋白质充当游离脂肪酸 (包括 omega-3) 的受体，并参与抑制抗炎反应和胰岛素敏化。已发现该基因编码不同异构体的多个转录变体。[RefSeq 提供，2012 年 2 月]

This gene encodes a G protein-coupled receptor (GPR) which belongs to the rhodopsin family of GPRs. The encoded protein functions as a receptor for free fatty acids, including omega-3, and participates in suppressing anti-inflammatory responses and Insulin sensitizing. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012]

FFAR4 基因产物(2)

mRNA Protein Name
NM_001195755.2 NP_001182684.1 free fatty acid receptor 4 isoform GPR120-S
NM_181745.4 NP_859529.2 free fatty acid receptor 4 isoform GPR120-L

FFAR4 蛋白结构

7tm_1

7tm_1: 7 transmembrane receptor (rhodopsin family) (57 - 337)

  • 0
  • 100
  • 200
  • 300
  • 377 a.a.
蛋白主名 其他名称

free fatty acid receptor 4

G-protein coupled receptor 120

关联疾病

疾病名称 别名
Body Mass Index Quantitative Trait Locus 10

Obesity

BMIQ10

Obesity, Susceptibility To
Body Mass Index Quantitative Trait Locus 11

OBESITY

Obesity, Susceptibility To

Leanness, Inherited

Obesity, Susceptibility To, Bmiq11

Obesity, Mild, Early-Onset

Obesity, Association With

Obesity, Early-Onset, Susceptibility To

Obesity, Severe

Obesity, Severe, And Type Ii Diabetes

Obesity, Late-Onset

Obesity , Susceptibility To

BMIQ11

Obesity Bmiq11

Obesity, Early-Onset

Simple Obesity Nos

Excess Fat

Obesity, Not Elsewhere Classified, Body Mass Index Not Elsewhere Classified

Adiposis
Diabetes Mellitus

Diabetes
Type 2 Diabetes Mellitus

Insulin Resistance

NIDDM

Type 2 Diabetes

Diabetes Mellitus, Non-Insulin-Dependent

T2D

Noninsulin-Dependent Diabetes Mellitus

Diabetes Mellitus, Type Ii

Maturity-Onset Diabetes

Insulin Resistance, Severe, Digenic

Diabetes Mellitus, Type 2

Diabetes Mellitus, Noninsulin-Dependent

Diabetes Mellitus, Noninsulin-Dependent, Association With

Diabetes Mellitus, Noninsulin-Dependent, Late Onset

Hypertension, Insulin Resistance-Related, Susceptibility To

Insulin Resistance, Susceptibility To

Non-Insulin-Dependent Diabetes Mellitus

Type Ii Diabetes Mellitus

Adult-Onset Diabetes Mellitus

Maturity-Onset Diabetes Mellitus

Diabetes Mellitus Type 2

Type Ii Diabetes

Type 2 Diabetes Mellitus, Susceptibility To

Diabetes, Type 2

Diabetes Mellitus, Noninsulin-Dependent, Susceptibility To

Diabetes Mellitus, Non-Insulin-Dependent, Susceptibility To

Diabetes Mellitus, Type 2, Susceptibility To

Diabetes Mellitus, Noninsulin-Dependent, 2

Diabetes Mellitus, Type Ii, Susceptibility To

Hypertension, Insulin Resistance-Related

Adult-Onset Diabetes

Aodm

Diabetes Mellitus, Adult-Onset

Diabetes Mellitus Type Ii

Diabetes Mellitus Type 2, Susceptibility To

Diabetes, Type Ii, Susceptibility To

Diabetes Type 2

Diabetes Mellitus

Adult Onset Diabetes

Maturity Onset Diabetes

Nonketotic Diabetes

Non-Insulin Dependent Diabetes Mellitus

T2dm - [Type 2 Diabetes Mellitus]

Niddm - [Non Insulin Dependent Diabetes Mellitus]

Dm2

Dm Type Ii

Diabetic Type 2

Insulin Requiring Type 2 Diabetes

Noninsulin Dependent Diabetes

Non-Insulin-Dependent Diabetes Mellitus Without Complications

Diabetes Due To Insulin Secretory Defect

Diabetes Mellitus Due To Insulin Secretory Defect

Non-Insulin-Dependent Diabetes Of The Young

Senile Diabetes

Nonketotic Hyperglycaemia

Stable Diabetes
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-N3977 Grifolic acid Agonist ≥98.0% 否
HY-114610 13Z,16Z-Docosadienoic acid Agonist / 否
HY-RS04877 FFAR4 Human Pre-designed siRNA Set A / 否

直系同源

种属 基因名 来源 基因 ID
Bos taurus FFAR4 VGNC VGNC:28962
Macaca mulatta FFAR4 VGNC VGNC:72532
Rattus norvegicus FFAR4 RGD RGD:1308252
Canis familiaris FFAR4 VGNC VGNC:40832
Mus musculus FFAR4 MGD MGI:2147577
Felis catus FFAR4 VGNC VGNC:62236
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z