1. Gene
  2. LINGO4 - leucine rich repeat and Ig domain containing 4 Gene

LINGO4 - leucine rich repeat and Ig domain containing 4 Gene

中文名称:含富亮氨酸的重复序列和 Ig 结构域 4

种属: Homo sapiens

同用名: LRRN6D; DAAT9248; PRO34002

基因 ID: 339398 | 基因类型: protein coding

关于 LINGO4

Cytogenetic location: 1q21.3 Genomic coordinates (GRCh38): 1:151,800,264-151,805,419 (from NCBI)

This gene has 1 transcript (splice variant), 367 orthologues and 10 paralogues. Broad expression in adrenal (RPKM 1.2), testis (RPKM 0.4) and 16 other tissues.

功能概要

预计在突触组装的正调节上游或正调节内起作用。预计是膜的组成部分。预计在细胞外基质和细胞外空间中具有活性。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to act upstream of or within positive regulation of synapse assembly. Predicted to be integral component of membrane. Predicted to be active in extracellular matrix and extracellular space. [provided by Alliance of Genome Resources, Apr 2022]

LINGO4 基因产物(1)

mRNA Protein Name
NM_001004432.4 NP_001004432.1 leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 4 precursor

LINGO4 蛋白结构

LRR_8

LRR_8: Leucine rich repeat (64 - 120)

LRR_8

LRR_8: Leucine rich repeat (157 - 212)

LRR_8

LRR_8: Leucine rich repeat (253 - 309)

I-set

I-set: Immunoglobulin I-set domain (420 - 501)

  • 0
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  • 500
  • 593 a.a.
蛋白主名 其他名称

leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 4

leucine-rich repeat neuronal protein 6D

关联疾病

疾病名称 别名
Essential Tremor

Benign Essential Tremor

Familial Tremor

Hereditary Essential Tremor

Essential Hereditary Tremor

Shaky Hand Syndrome

Benign Essential Tremor Syndrome

Tremor Hereditary Essential

Essential Tremor, Susceptibility To

Tremor, Hereditary Essential

Tremor, Hereditary Essential, 5

ETM5

Essential Tremor 5

Essential Tremor, Hereditary, 5

Hereditary Essential Tremor 5

Tremor, Hereditary Essential 5

Tremor, Essential Hereditary, Type 5

Tremor, Hereditary Essential, 4

ETM4

Essential Tremor 4

Essential Tremor, Hereditary, 4

Hereditary Essential Tremor 4

Tremor, Hereditary Essential 4

Tremor, Hereditary Essential, Type 4

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Felis catus LINGO4 VGNC VGNC:63238
Bos taurus LINGO4 VGNC VGNC:30902
Mus musculus LINGO4 MGD MGI:2444651
Macaca mulatta LINGO4 VGNC VGNC:74171
Canis familiaris LINGO4 VGNC VGNC:42691
Rattus norvegicus LINGO4 RGD RGD:1562025