DCDC1 - doublecortin domain containing 1 Gene

中文名称：含双肾上腺皮质激素域 1

种属: Homo sapiens

同用名: DCDC5

基因 ID: 341019 | 基因类型: protein coding

关于 DCDC1

Cytogenetic location: 11p14.1-p13 Genomic coordinates (GRCh38): 11:30,863,603-31,369,739 (from NCBI)

This gene has 12 transcripts (splice variants) and 57 orthologues. Biased expression in testis (RPKM 2.0), thyroid (RPKM 0.3) and 3 other tissues.

功能概要

该基因编码 doublecortin 家族的一个成员。该基因编码的蛋白质是一种亲水性细胞内蛋白质。它包含一个双皮质素结构域，不能结合微管和调节微管聚合。该基因主要在成人睾丸中表达。它没有小鼠同系物。[RefSeq 提供，2010 年 9 月]

This gene encodes a member of the doublecortin family. The protein encoded by this gene is a hydrophilic, intracellular protein. It contains a single doublecortin domain and is unable to bind microtubules and to regulate microtubule polymerization. This gene is mainly expressed in adult testis. It does not have a mouse homolog. [provided by RefSeq, Sep 2010]

DCDC1 基因产物(5)

mRNA	Protein	Name
NM_001367979.1	NP_001354908.1	doublecortin domain-containing protein 1 isoform 4
NM_001387274.1	NP_001374203.1	doublecortin domain-containing protein 1 isoform 6
NM_001387275.1	NP_001374204.1	doublecortin domain-containing protein 1 isoform 7
NM_020869.4	NP_065920.2	doublecortin domain-containing protein 1 isoform 3
NM_181807.4	NP_861523.2	doublecortin domain-containing protein 1 isoform 2

基因本体论

分子功能
生物过程
细胞组分

分子功能 GO 注释	逻辑证据	参考文献	来源
enables microtubule binding	IDA IDA: 通过直接分析推断	22159412	GOA
enables protein binding	IPI IPI: 通过物理相互作用推断	22159412	GOA

生物过程 GO 注释	逻辑证据	参考文献	来源
involved in regulation of mitotic cytokinesis	IMP IMP: 通过突变表型推断	22159412	GOA

细胞组分 GO 注释	逻辑证据	参考文献	来源
located in Flemming body	IDA IDA: 通过直接分析推断	22159412	GOA
located in midbody	IDA IDA: 通过直接分析推断	22159412	GOA
located in mitotic spindle	IDA IDA: 通过直接分析推断	22159412	GOA

EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

蛋白主名

其他名称

doublecortin domain-containing protein 1

doublecortin domain-containing 5 protein

关联疾病

疾病名称

别名

Brachyolmia Type 4 With Mild Epiphyseal And Metaphyseal Changes

Spondyloepimetaphyseal Dysplasia, Pakistani Type	Spondyloepimetaphyseal Dysplasia, Papss2 Type
BCYM4	Semd, Pakistani Type
Spondylodysplasia And Premature Pubarche	Brachyolmia 4 With Mild Epiphyseal And Metaphyseal Changes
Spondyloepimetaphyseal Dysplasia Pakistani Type	Semd Pakistani Type
Spondylometaepiphyseal Dysplasia Pakistani Type	Brachyolmia, Type 4, With Mild Epiphyseal And Metaphyseal Changes

Wilms Tumor, Aniridia, Genitourinary Anomalies, And Mental Retardation Syndrome

Wagr Syndrome	11p Partial Monosomy Syndrome
Chromosome 11p13 Deletion Syndrome	Wilms Tumor, Aniridia, Genitourinary Anomalies And Mental Retardation Syndrome
11p Deletion Syndrome	Chromosome 11p Deletion Syndrome
Wagr Complex	Wilms Tumor-Aniridia-Genitourinary Anomalies-Intellectual Disability Syndrome
Deletion 11p13	WAGR
Wilms Tumor-Aniridia-Genitourinary Anomalies-Mental Retardation Syndrome	Chromosome 11p Deletion
11p Deletion	11p Monosomy
Deletion 11p	Monosomy 11p
Partial Monosomy 11p	Agr Triad
Wilms Tumor-Aniridia-Gonadoblastoma-Mental Retardation Syndrome	Wilms Tumor, Aniridia, Genitourinary Anomalies, Mental Retardation Syndrome
Wagr Contiguous Gene Syndrome	Wilms Tumor-Aniridia-Genital Anomalies-Retardation Syndrome
Wilms Tumor-Aniridia-Genitourinary Anomalies-Mr Syndrome	Del(11)(P13)
Monosomy 11p13	Chromosome 11, Deletion 11p

Iris Disease

Iris Diseases

Aniridia 1

Aniridia	Congenital Aniridia
AN1	An
Cataract With Late-Onset Corneal Dystrophy	Aplasia Of Iris
Absent Iris	Irideremia
Aniridia Ii, Formerly	An2, Formerly
An2	Aniridia Type Ii
Aniridia, Type 1	An-1
Absence Of Iris	Agenesis Of Iris
Congenital Absence Of Iris	Hereditary Aniridia
Sporadic Aniridia

Coloboma Of Optic Nerve

Morning Glory Disc Anomaly	Coloboma Of Optic Disc
Morning Glory Syndrome	Ectasic Coloboma
Coloboma Of Optic Papilla	Congenital Coloboma Of The Optic Nerve
Optic Nerve Coloboma	Optic Nerve Head Pits, Bilateral Congenital
Volubilis Syndrome	COLON
Coloboma Of Optic Disc, Unspecified Eye	Congenital Coloboma Of Optic Disc
Optic Disk Coloboma

Band Heterotopia

Subcortical Band Heterotopia	Double Cortex Syndrome
Subcortical Laminar Heterotopia	Double Cortex
Band Heterotopia Of Brain	BH
Heco	Heterotopic Cortex
Familial Band Heterotopia	Dc
Dc Syndrome	Heterotopia, Subcortical Band
Sbh	Sclh
Bhy

Benign Epilepsy With Centrotemporal Spikes

Rolandic Epilepsy	Benign Rolandic Epilepsy
Epilepsy, Rolandic	Bcects
Benign Childhood Epilepsy With Centrotemporal Spike	Sylvan Seizures
Becrs	Bects
Bre	Benign Epilepsy Of Childhood With Centrotemporal Spikes
Benign Familial Epilepsy Of Childhood With Rolandic Spikes	Centrotemporal Epilepsy

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-RS03573	DCDC1 Human Pre-designed siRNA Set A	Pre-designed Set	/	否

直系同源

种属	基因名	来源	基因 ID
Bos taurus	DCDC1	VGNC	VGNC:108127
Canis familiaris	DCDC1	VGNC	VGNC:106595
Rattus norvegicus	DCDC1	RGD	RGD:1562221

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MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。

站点地图隐私声明

沪ICP备15051369号-4

上海工商

沪公网安备31011502019417

沪(浦)应急管危经许[2021]201709(QFYS)

营业执照（三证合一）

DCDC1 - doublecortin domain containing 1 Gene

关于 DCDC1

功能概要

DCDC1 基因产物(5)

关联疾病

直系同源

热门区域

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DCDC1 - doublecortin domain containing 1 Gene

关于 DCDC1

功能概要

DCDC1 基因产物(5)

关联疾病

相关产品

直系同源

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z