QRFP - pyroglutamylated RFamide peptide Gene

中文名称：焦谷氨酰化 RFamide 肽

种属: Homo sapiens

同用名: P518; 26RFa

关于 QRFP

功能概要

该基因编码一种前原蛋白，该蛋白经过蛋白水解处理可产生多种蛋白质产物。编码的产物是 RFamide 神经肽家族的成员，其特征在于它们共同的蛋白质 C 末端由精氨酸 (R) 和酰胺化苯丙氨酸 (F) 组成。这些产品包括神经肽 26RFa 和 N 末端延伸形式 43RFa。这两种神经肽都与焦谷氨酰化 RF 酰胺肽受体 (QRFPR) 结合，可以调节啮齿动物的血压、繁殖和食物摄入。[RefSeq 提供，2015 年 7 月]

This gene encodes a preproprotein that is proteolytically processed to generate multiple protein products. The encoded products are members of the RFamide family of neuropeptides, characterized by their common protein C-terminus consisting of an arginine (R) and an amidated phenylalanine (F). These products include the neuropeptides 26RFa and the N-terminally extended form, 43RFa. Both of these neuropeptides bind to the pyroglutamylated RFamide peptide receptor (QRFPR) and may regulate blood pressure, reproduction and food intake in rodents. [provided by RefSeq, Jul 2015]