2. Gene
  3. AMIGO2 - adhesion molecule with Ig like domain 2 Gene

AMIGO2 - adhesion molecule with Ig like domain 2 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：具有 Ig 样结构域 2 的粘附分子

种属: Homo sapiens

同用名: ALI1; DEGA; AMIGO-2

基因 ID: 347902 | 基因类型: protein coding

关于 AMIGO2

Cytogenetic location: 12q13.11 Genomic coordinates (GRCh38): 12:47,075,707-47,079,959 (from NCBI)

This gene has 3 transcripts (splice variants), 168 orthologues and 2 paralogues. Broad expression in gall bladder (RPKM 9.4), urinary bladder (RPKM 8.8) and 23 other tissues.

功能概要

预计参与多个过程，包括通过质膜细胞粘附分子的异嗜性细胞间粘附；通过质膜粘附分子的嗜同细胞粘附；和程序性细胞死亡的负调节。预计在突触组装的正调节上游或正调节内起作用。预测位于细胞核和质膜。预计是膜的组成部分。胃腺癌的生物标志物。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to be involved in several processes, including heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules; homophilic cell adhesion via plasma membrane adhesion molecules; and negative regulation of programmed cell death. Predicted to act upstream of or within positive regulation of synapse assembly. Predicted to be located in nucleus and plasma membrane. Predicted to be integral component of membrane. Biomarker of gastric adenocarcinoma. [provided by Alliance of Genome Resources, Apr 2022]

AMIGO2 基因产物(3)

mRNA Protein Name
NM_001143668.1 NP_001137140.1 amphoterin-induced protein 2 precursor
NM_001370299.1 NP_001357228.1 amphoterin-induced protein 2 precursor
NM_181847.4 NP_862830.1 amphoterin-induced protein 2 precursor

AMIGO2 蛋白结构

LRR_8

LRR_8: Leucine rich repeat (94 - 153)

LRR_1

LRR_1: Leucine Rich Repeat (166 - 183)

Ig_2

Ig_2: Immunoglobulin domain (300 - 378)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 522 a.a.
蛋白主名 其他名称

amphoterin-induced protein 2

alivin 1

重组 AMIGO2 蛋白

目录号 产品名 蛋白编号 纯度
HY-P7495 AMIGO2 Protein, Human (HEK293, His) Q86SJ2 (V40-A392) ≥95%
HY-P7496 AMIGO2 Protein, Human (HEK293, Fc) Q86SJ2 (G39-H393) ≥95%

关联疾病

疾病名称 别名
Gastric Adenocarcinoma

Adenocarcinoma Of Stomach

Stomach Adenocarcinoma

Adenocarcinoma Gastric

Intestinal Type Adenocarcinoma Of Unspecified Site

Diffuse Type Adenocarcinoma Of Unspecified Site
Adenocarcinoma

Adenocarcinomas

Adenoacanthoma Of Unspecified Site

Adenocarcinoid Of Unspecified Site

Adenocarcinoid Tumour Of Unspecified Site

Adenocarcinoma And Carcinoid Combined Of Unspecified Site

Adenocarcinoma Nos
Parkinson Disease 8, Autosomal Dominant

Parkinson Disease 8

Autosomal Dominant Parkinson Disease 8

PARK8

Parkinson'S Disease 8

Autosomal Dominant Parkinson'S Disease 8

Parkinson Disease-8

Parkinson Disease, Type 8, Autosomal Dominant
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS00658 AMIGO2 Human Pre-designed siRNA Set A / 否

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta AMIGO2 VGNC VGNC:69680
Rattus norvegicus AMIGO2 RGD RGD:727911
Mus musculus AMIGO2 MGD MGI:2145995
Bos taurus AMIGO2 VGNC VGNC:25866
Felis catus AMIGO2 VGNC VGNC:59766
Canis familiaris AMIGO2 VGNC VGNC:37832
Macaca fascicularis AMIGO2 NCBI
Others AMIGO2 NCBI
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